Hodgkin lymphoma associated vanishing bile duct syndrome treated successfully with a brentuximab based regimen
Judah D Morgan,
Robert C Weishar,
Ryan M Kwok
et al.
Abstract:We report a combination therapy to successfully treat a patient with Hodgkin’s lymphoma complicated by vanishing bile duct syndrome. Our patient was in his 20s and presented with jaundice, emesis, B symptoms and diffuse lymphadenopathy along with cholestatic liver injury prompting a liver biopsy, which revealed this diagnosis, after the exclusion of other aetiologies. Our treatment regimen incorporated brentuximab along with other more conventional agents which attempted to maximise therapeutic efficacy while … Show more
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