Hodgkin disease, the non-Hodgkin lymphomas, and the leukemias in the retroperitoneum

Castellino, Ronald A.; Marglin, Stephen I.; Blank, Norman

doi:10.1016/0037-198x(80)90025-5

Cited by 25 publications

(8 citation statements)

References 25 publications

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“…6,10,11,14,[24][25][26] In our study, no differences were seen between lymphoma and solid tumors according to the presence of other organ involvement. In other words, when we detected a splenic tumor, there were no differences between lymphoma and solid tumors regarding the presence of other organ involvement.…”

Section: 7contrasting

confidence: 66%

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Ozen¹

2015

UHOD

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Splenic involvement guide treatment and affect prognosis in lymphoma and solid tumors. The most common used imaging techniques in detecting splenic involvement are Ultrasound (US) and Computed Tomography (CT). In this study, our aims were to evaluate the imaging findings regarding the spleen, compare splenic lesions according to the diagnosis and evaluate correlations between US and CT according to splenomegaly and lesions. Between May 2008 and April 2011 we identified 72 patients with splenic lesions or splenomegaly on CT or US. However, we exclude 27 patients from the study because of study protocol. Therefore, we enrolled 45 patients with a proven malignancy who had splenic lesions detected with CT. Seventeen patients had a diagnosis of lymphoma, and 28 patients had non-hematological malignancies. The characteristic features of the splenic lesions, detected on CT in patients with a proven malignancy, varied according to the cancer type. Multiple splenic lesions and splenomegaly in lymphoma patients and only solitary lesions in solid tumors were seen on CT (p< 0.001). Lymphoma patients usually had a solid splenic lesion with splenomegaly on US, but no lesion in solid tumors were seen on US (p< 0.05). The US and CT correlation ratio was inferior for solid tumors.US may miss splenic solid tumor metastases. CT is useful for distinguishing splenic lymphoma involvement from solid tumor metastases. CT seems superior to US in detecting splenic solid tumor metastases.Keywords: Spleen, Ultrasound, Computed Tomography, Lymphoma, Solid Malignancies ÖZET Lenfoma ve Solid Tümörlerde Dalağın Malign Lezyonları, Görüntüleme Teknikleri Kıyaslama ÇalışmasıLenfoma ve solid tümörlerde dalak tutulumu prognozu etkilemekte ve tedaviye klavuzluk etmektedir. Dalak tutulumunun tanımlanmasında en sık kullanılan görüntüleme teknikleri Ultrason (US) ve Bilgisayarlı Tomografi (BT)'dir. Bu çalışmada dalağın görüntüleme bulgularını değerlendirmeyi, tanıya göre dalak lezyonlarını kıyaslamayı ve splenomegali ve lezyonlara göre US ve BT arasındaki korelasyonu değerlendirmeyi amaçladık. Mayıs 2008 ve Nisan 2011 arasında BT veya US'de splenomegali veya dalak lezyonları olan 72 hasta tanımladık. Ancak, 27 hastayı çalışma protokolü nedeniyle çalışmadan çıkarttık. Sonuçta kanıtlanmış bir malignensisi olan ve BT ile dalakta lezyonu saptanmış 45 hastayı çalışmaya aldık. On yedi hastanın tanısı lenfoma, 28 hastanın tanısı ise hematolojik olmayan malignensi idi. Kanıtlanmış bir malignensisi olan hastalarda BT'de gözlenen dalak lezyonlarının karakteristik özel-likleri kanser tipine göre farklılık gösterdi. BT'de lenfoma hastalarında dalakta çok sayıda lezyonla birlikte splenomegali görülürken, solid tümörlerde yalnızca tek lezyon görüldü (p< 0.001). US'de lenfoma hastalarında genellikle bir solid lezyona eşlik eden splenomegali varken, solid tümörlerde US'de lezyon gözlenmedi (p< 0.05). US ve BT'nin korelasyon oranı solid tümörlerde düşüktü. US solid tümör metastazını gözden kaçırabilir. BT lenfomanın dalak tutulumunu solid tümörlerin dalak metas...

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Section: 7contrasting

confidence: 66%

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Ozen¹

2015

UHOD

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“…14 However, splenomegaly is not a reliable indicator of lymphomatous involvement of the spleen because the organ size is normal in one-third of patients with splenic lymphoma. 15 Furthermore, most of the patients also have concomitant involvement of the liver and or lymph nodes at the time of diagnosis, even though splenomegaly may be the main presenting feature of lymphoma. 16 In these circumstances, the definition of PSL is controversial.…”

Section: Figurementioning

confidence: 99%

Primary Splenic Lymphoma Detected by F-18 FDG PET

Takata¹,

Kaida²,

Ishibashi³

et al. 2008

Clinical Nuclear Medicine

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F-18 FDG uptake of splenic involvement by malignant lymphoma has frequently been seen, but reports of F-18 FDG PET related to primary splenic lymphoma (PSL) are very rare. We describe herein a case of PSL detected by F-18 FDG PET. A 66-year-old woman was referred for further examination due to indications of a solitary splenic tumor. F-18 FDG PET revealed the abnormal focal uptake of the spleen. Laparoscopic splenorectomy was performed to acquire the histopathological findings. The histopathological findings of splenic tumor were diffuse large B-cell lymphoma.

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“…Virtually all NHLs are neoplasms of lymphocytes and their derivatives, the morphologic diversities of which reflect various stages in lymphocyte development and transformation (2,3,5).…”

mentioning

confidence: 99%

“…Although NHL is predominantly a malignant tumor of lymph nodes, in contrast to Hodgkin's lymphoma, involve ment of other tissues can occur frequently either at the initial presentation of the disease or during a subsequent recurrence (1,3,5,6,8,(10)(11)(12)(13); NHL in extranodal site often is an example of localized disease showing intermediate or high-grade histology with or without regional lymphade nopathy. Whereas manifestations of NHL in the Waldeyer ring, the gastrointestinal tract and the liver are well known, hematopoietic tumors of the pancreas, except for lymphoblastic (Burkitt's) lymphoma, are rare (2,4,5,8,15).…”

mentioning

confidence: 99%

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CT in Pancreatic Involvement of Non-Hodgkin Lymphoma

Prayer¹,

Schurawitzki²,

Mallek³

et al. 1992

Acta Radiol

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In an attempt to evaluate characteristic CT features of primary pancreatic involvement in non-Hodgkin lymphoma (NHL), scans of 10 patients were reviewed retrospectively and compared to 50 patients with histologically proved different neoplasms of the pan creas. Setting the correct diagnosis of NHL would be essential for planning of treatment and prognosis. CT findings of NHL were characteristic but not specific. Nevertheless, the presence of a homo geneous pancreatic mass with a diameter of 7 cm or more, infiltrat ing surrounding tissue accompanied by retroperitoneal and/or mesenteric lymphadenopathy strongly suggests NHL. CT-guided needle biopsy can help to establish the diagnosis of pancreatic NHL.

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Hodgkin disease, the non-Hodgkin lymphomas, and the leukemias in the retroperitoneum

Cited by 25 publications

References 25 publications

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Primary Splenic Lymphoma Detected by F-18 FDG PET

CT in Pancreatic Involvement of Non-Hodgkin Lymphoma

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