HoBi-like pestivirus infection in an outbreak of bovine respiratory disease

Hoppe, Ingrid Bortolin Affonso Lux; Pollo, Andressa de Souza; Medeiros, Andrea; Samara, Samir Issa; Carvalho, Adolorata Aparecida Bianco

doi:10.1016/j.rvsc.2019.09.003

Cited by 13 publications

(12 citation statements)

References 44 publications

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“…HoBilike pestivirus, an emerging agent initially identified in Europe in fetal bovine serum imported from Brazil, was related to respiratory manifestations, inducing viremia, leukopenia, fever, and nasal secretions (Bauermann, Ridpath, Weiblen, & Flores, 2013). Additionally, HoBi-like pestivirus was associated with the development of pneumonia in a calf from Italy (Decaro, Mari, Pinto, Lucente, & Sciarretta, 2012) and in several calves from an outbreak of BRD in São Paulo (Hoppe et al, 2019).…”

Section: Etiological Agents Associated With the Development Of Brd In Brazilmentioning

confidence: 99%

“…Additionally, there is evidence that ovine gammaherpesvirus-2, OvHV-2 and HoBi-like pestiviruses (Hoppe et al, 2019) are candidates of emerging pathogens associated with the development of BRD. Recently, OvHV-2 was associated with the occurrence of respiratory disease in a calf infected simultaneously with BVDV, BoHV-1, and Aspergillus fumigatus (Headley, Müller, Oliveira, Duarte, & Pereira, 2020) and in two adult cattle with interstitial pneumonia (Headley, Oliveira, Li, Lisbôa, & Queiroz, 2020).…”

Section: Bacterialmentioning

confidence: 99%

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Bovine respiratory disease in Brasil: a short review

Castro¹,

Oliveira²,

Headley³

2021

Semina: Ciênc. Agrár.

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The bovine respiratory disease (BRD) complex is a multifactorial and multietiological disease entity described in all geographic regions of Brazil. This brief review discusses aspects related to epidemiology, etiologic agents, clinical and pathological manifestations, and challenges in the diagnosis of BRD in Brazil. The main infectious disease agents associated with respiratory outbreaks in cattle from Brazil are bovine alphaherpesvirus type 1, bovine viral diarrhea virus, bovine respiratory syncytial virus, and Mycoplasma bovis. Ovine gammaherpesvirus-2 and HoBi-like pestivirus have been associated with the development of pneumonia in adult cattle and calves, respectively in Brazil, and should be considered as possible causes of BRD. Additionally, studies using epidemiological data, histopathological and molecular associations with morbidity and mortality should be carried out in Brazil, to demonstrate the real impacts of BRD on livestock.

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Section: Etiological Agents Associated With the Development Of Brd In Brazilmentioning

confidence: 99%

Section: Bacterialmentioning

confidence: 99%

Bovine respiratory disease in Brasil: a short review

Castro¹,

Oliveira²,

Headley³

2021

Semina: Ciênc. Agrár.

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“…On the basis of the nucleotide sequence of the 5′UTR or the E2 gene, isolates are categorized into genotypes or subgenotypes. While the 5′UTR is the most conserved region in pestiviruses and is often used for viral detection for diagnosis, the E2 gene, which encodes a major target of neutralizing antibodies, is the most variable and used for comparative genomic analysis [ 3 , 4 ]. There are two types of BVDV infection: transient infection and persistent infection.…”

Section: Introductionmentioning

confidence: 99%

Transmission Dynamics of Bovine Viral Diarrhea Virus in Hokkaido, Japan by Phylogenetic and Epidemiological Network Approaches

et al. 2021

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Bovine viral diarrhea (BVD) caused by BVD virus (BVDV) leads to economic loss worldwide. Cattle that are persistently infected (PI) with BVDV are known to play an important role in viral transmission in association with the animal movement, as they shed the virus during their lifetime. In this research, the “hot spot” for BVD transmission was estimated by combining phylogenetic and epidemiological analyses for PI cattle and cattle that lived together on BVDV affected farms in Tokachi district, Hokkaido prefecture, Japan. Viral isolates were genetically categorized into BVDV-1a, 1b, and 2a, based on the nucleotide sequence of the entire E2 region. In BVDV genotype 1, subgenotype b (BVDV-1b), cluster I was identified as the majority in Tokachi district. Network analysis indicated that 12 of the 15 affected farms had cattle movements from other facilities (PI-network) and farms affected with BVDV-1b cluster I consisted of a large network. It was implied that the number of cattle movements themselves would be a risk of BVD transmission, using the PageRank algorithm. Therefore, these results demonstrate that cattle movements would contribute to disease spread and the combination of virological and epidemiological analysis methods would be beneficial in determining possible virus transmission routes.

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“…HoBiPeV was first isolated from a contaminated batch of fetal bovine serum (FBS) from Brazil (7) and later detected in a contaminated cell culture and the blood of a buffalo in South America (8). Further HoBiPeV infections were reported in Thailand, Italy, Bangladesh, India, Argentina, China, and Turkey (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). However, while viruses circulating in South America, Europe, Thailand and China are closely related, other Asian HoBiPeV strains are highly divergent and at least four different subtypes have been identified so far (3).…”

Section: Introductionmentioning

confidence: 99%

“…However, while viruses circulating in South America, Europe, Thailand and China are closely related, other Asian HoBiPeV strains are highly divergent and at least four different subtypes have been identified so far (3). HoBiPeV infection has the same outcomes reported for BVDV-1 and BVDV-2, including immunosuppression, respiratory disease, gastroenteritis, persistent infections, mucosal disease, and reproductive disorders (10,15,(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30). The most relevant economic losses associated with BVDV-1 and BVDV-2 infection are due to reproductive disorders.…”

Section: Introductionmentioning

confidence: 99%

HoBi-Like Pestivirus and Reproductive Disorders

Decaro

2020

Front. Vet. Sci.

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HoBi-like pestivirus (HoBiPeV) is an emerging group of pestiviruses that has been detected in cattle and other ruminants in South America, Europe, and Asia. Analogous to other bovine pestiviruses, namely bovine viral diarrhea (BVDV) 1 and 2, HoBiPeV is able to cause a variety of clinical forms that range from asymptomatic infections to fatal disease, having a great impact on cattle productions and causing substantial economic losses, mainly as a consequence of the occurrence of reproductive failures. The manuscript aims to provide an updated review of the currently available literature about the impact of HoBiPeV infection on cattle reproduction. The reproductive disorders observed in cattle due to natural and experimental infections caused by this virus are reported along with the few available in-vitro studies involving the reproductive tract. HoBiPeV should be considered among the bovine pathogens that impact on reproduction, but there is a need for more specific and sensitive diagnostic methods, while the cross-protection elicited by commercially available BVDV vaccines should be better investigated.

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HoBi-like pestivirus infection in an outbreak of bovine respiratory disease

Cited by 13 publications

References 44 publications

Bovine respiratory disease in Brasil: a short review

Bovine respiratory disease in Brasil: a short review

Transmission Dynamics of Bovine Viral Diarrhea Virus in Hokkaido, Japan by Phylogenetic and Epidemiological Network Approaches

HoBi-Like Pestivirus and Reproductive Disorders

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