2011
DOI: 10.1016/j.jocn.2010.07.150
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Hoarseness in pellagra

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Cited by 9 publications
(4 citation statements)
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References 6 publications
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“…Severe alcoholism can likewise exert a negative effect on niacin production 19 24 . Chronic alcoholism may cause inadequate intake of protein (tryptophan) and vitamin B, inhibition of Trp 2,3‐dioxygenase activity by an NAD(P)H‐mediated allosteric mechanism, and repression of kynurenine aminotransferase and kynureninase activities by acetaldehyde through binding of their pyridoxal 5'‐phosphate cofactor and thereby lead to disturbance of the kynurenine pathway 5 …”
Section: Discussionmentioning
confidence: 99%
“…Severe alcoholism can likewise exert a negative effect on niacin production 19 24 . Chronic alcoholism may cause inadequate intake of protein (tryptophan) and vitamin B, inhibition of Trp 2,3‐dioxygenase activity by an NAD(P)H‐mediated allosteric mechanism, and repression of kynurenine aminotransferase and kynureninase activities by acetaldehyde through binding of their pyridoxal 5'‐phosphate cofactor and thereby lead to disturbance of the kynurenine pathway 5 …”
Section: Discussionmentioning
confidence: 99%
“…2 In this issue of the Journal of Clinical Neuroscience, Hiraga et al present an interesting patient with pellagra who has laryngitis and hoarseness. 3 Although patients with pellagra are known to have oral lesions such as stomatitis and glossitis, this is the first report of pellagra causing laryngitis. The patient is a 67-year-old woman with chronic alcoholism.…”
Section: Introductionmentioning
confidence: 84%
“…A deficiency in niacin manifests itself with the disease, pellagra [30][31][32][33]. It is frequently associated with alcoholism as well as glossitis, scarlet stomatitis, diarrhea, dermatitis, and psychosis, as well as mental deficiency.…”
Section: Discussionmentioning
confidence: 99%