HLA Polymorphism in Israel

Bonné‐Tamir, Batsheva; Bodmer, JG; Modai, J.

doi:10.1111/j.1399-0039.1978.tb01252.x

Cited by 6 publications

(1 citation statement)

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“…83 After securing the cooperation of teachers at the Armenian Theological Seminary and St. Tarkmanchatz School, Bonné led weekly trips with Tel Aviv medical students to the Armenian quarter, collecting blood from twenty seminary students and 140 high school students. 84 Bonné treated the Old City Armenian Quarter as an isolated community somehow immune to the effects of Israeli-Palestinian violence, mentioning only that "about half of them are descendents [sic] of the original Armenians and the rest are later 'joiners'" (i.e., refugees from 1948). She provided no further elaboration or analytical acknowledgment of either this original-latecomer distinction, or the recent historical events, including Israeli state policies, that had produced this population structure.…”

Section: " E S S E N T I a L C O L L A B O R A T O R S " 143mentioning

confidence: 99%

“Essential Collaborators”: Locating Middle Eastern Geneticists in the Global Scientific Infrastructure, 1950s–1970s

Burton

2018

Comp Stud Soc Hist

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In the aftermath of World War II, a new international infrastructure based on United Nations agencies took charge of coordinating global biomedical research. Through this infrastructure, European and American geneticists hoped to collect and test blood samples from human populations across the world to understand processes of human heredity and evolution and trace the historical migrations of different groups. They relied heavily on local scientific workers to help them identify and access populations of interest, although they did not always acknowledge the critical role non-Western collaborators played in their studies. Using scientific publications, personal correspondence, and oral histories, I investigate the collaborative relationships between Western scientists, their counterparts in the Middle East, and the human subjects of genetic research. I comparatively examine the experiences of Israeli and Iranian scientists and physicians engaged in genetic anthropology and medical genetics between the mid-1950s and the late 1970s, noting how they both applied nationalist historical narratives to their genetic data and struggled to establish the value of their local knowledge and scientific labor. I argue that the Israeli and Iranian experience of transnational scientific collaboration is representative of how Western scientists relegated their collaborators from “developing” regions to a subordinate positionality as collection agents or native informants. Meanwhile, within their own countries, the elite professional identity of Israeli and Iranian scientists granted them the authority to manipulate their research subjects, who often belonged to marginalized minority communities, and to interpret their biology and history within contexts of Jewish and Persian nationalism.

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Section: " E S S E N T I a L C O L L A B O R A T O R S " 143mentioning

confidence: 99%

“Essential Collaborators”: Locating Middle Eastern Geneticists in the Global Scientific Infrastructure, 1950s–1970s

Burton

2018

Comp Stud Soc Hist

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Genetic polymorphisms among Bukharan and Georgian Jews in Israel

Levene¹,

Steinberg

Friedlander

et al. 1984

Am. J. Med. Genet.

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Bukharan and Georgian Jews have lived in central Asia for many centuries. Approximately 30,000 Bukharan and 37,000 Georgian Jews lived in their respective countries within the USSR between 1920 and 1960. Genetic markers of blood--blood groups, isoenzymes, HLA antigens, and gamma and kappa chain allotypes--were tested in blood samples from 113 Bukharan and 134 Georgian Jews living in Israel. Estimates of inbreeding were low: alpha = 0.0088 for Bukharan and alpha = 0.0011 for Georgian Jews. G6PD deficiency was relatively rare in Bukharan (2.2%) and in Georgian Jews (6.0%), when compared to other Jews in the area. Both populations showed frequencies of some markers similar to that of other Jewish populations, but frequencies of several markers were extremely high or low. Bukharan Jews showed very high frequencies of B(0.243), cDe (0.122), JkA (0.705), HLA-A29 (0.167), A30 (0.116) and B7 (0.124), and AcPA (0.451) and very low ones of O(0.518), CDe(0.422), AcPB (0.513) and GLO1 (0.140). Very high frequencies in Georgian Jews were observed for cDE (0.189), HLA-A3 (0.194), Bw35 (0.300) and GLO1 (0.367). Yet the greatest difference between both populations was in African characters. While in Bukharan Jews Fy was very frequent (0.146) and cDe was the highest observed among Jews (0.122), neither of these markers was detected among the Georgian Jews tested. Yet, another African character, the Gm1,5,10,11,13,14,17,26 haplotype, occurred in both populations (0.028 and 0.042 in Bukharan and Georgian Jews, respectively). Distance measures for Bukharan, Georgian, Iranian, Cochin, and Libyan Jews based on 13 polymorphic loci showed the greatest distance between Cochin Jews and the other populations and the smallest distance between the Georgian and Iranian Jews.

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Dating the Origin of the V170M Mutation Causing Non-Type I Cystinuria in Libyan Jews by Linkage Disequilibrium and Physical Mapping of the SLC7A9 Gene

Colombo

2000

Genomics

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HLA Polymorphism in Israel

Cited by 6 publications

References 1 publication

“Essential Collaborators”: Locating Middle Eastern Geneticists in the Global Scientific Infrastructure, 1950s–1970s

“Essential Collaborators”: Locating Middle Eastern Geneticists in the Global Scientific Infrastructure, 1950s–1970s

Genetic polymorphisms among Bukharan and Georgian Jews in Israel

Dating the Origin of the V170M Mutation Causing Non-Type I Cystinuria in Libyan Jews by Linkage Disequilibrium and Physical Mapping of the SLC7A9 Gene

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