HLA frequency distribution of the Portuguese bone marrow donor registry
Eduardo Espada,
Dário Ligeiro,
Hélder Trindade
et al.
Abstract:IntroductionThe Portuguese donor Registry of CEDACE was the fifth largest per capita bone marrow donor Registry of the WMDA as of 2019 and has yet to be thoroughly analyzed. We aimed to characterize its various aspects, including demographics and HLA allele and haplotype frequencies, to evaluate the genetic matching propensity score and ultimately further develop it.MethodsWe described and compared characteristics of the donor population with census data and used an Expectation-Maximization algorithm and analy… Show more
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