“…Previous data regarding HLA-E variation demonstrated that we usually find HLA-E coding sequences encoding two main molecules, named E ⁄ 01:01 and E ⁄ 01:03, differing by a single amino acid at codon 107, related to the non-synonymous mutation at the HLA-E position +756 or the genomic position 6:30.458.064 (Table 1) [14,15,17,18]. The first HLA-E protein, E ⁄ 01:01, is characterized by the presence of an Arginine at position 107 and it is encoded by alleles carrying an Adenine at position +756.…”