HL-A 27 and acute anterior uveitis.

Anterior Uveitis and Hypopyon

“…In terms of HLA association, 9 (82%) of the 11 patients with AAU in whom hypopyon developed were positive for HLA-B27. Two of these HLA-B27-positive patients had Reiter's syndrome and one had ankylosing spondylitis; all three of these patients were male.…”

Seasonal variation of endogenous uveitis in south‐western Finland

“…G eography and race (Schlaegel, Jr. 1984) and genetic factors (Brewerton et al 1973;Ehlers et al 1974;Mapstone & Woodrow 1975) play an important role in the epidemiology and etiology of uveitis. It has been shown that enteritic and urogenital infections may trigger acute anterior uveitis (AAU) in HLA-B27 positive patients (Saari & Kauranen 1980;Saari et al 1980a, b;1981;1986), some infectious agents, e.g., varicella virus may cause AAU also in HLA-B27 negative patients (Saari et al 1981), and many protozoa, viruses, bacteria, fungi, and parasitic worms may cause different types of infectious uveitis (Nussenblatt & Palestine.…”

Circulating Immune Complexes in Acute Uveitis: A Possible Association with the Histocompatibility Complex Locus Antigen B27

“…Acute anterior uveitis (AAU) may be associated with the human IC-mediated diseases, ser um sickness [3] and systemic lupus erythe matosus and also occurs in experimental serum sickness models. The role of ICs in human disease and methods used in their detection have been reviewed elsewhere [3,4], The histocompatibility complex antigen B27 is detected in over 90°/o of patients with ankylosing spondylitis [5], a condition fre quently accompanied by AAU, and has also been identified in up to 58% of patients pre senting de novo with AAU [5,6].…”