“…The introduction of HAART has not only resulted in significant decline in mortality associated with HIV across the world, significant reduction was also seen in the prevalence of most AIDS-defining illnesses and opportunistic infections (Buchacz et al, 2010;Kaplan et al, 2000;Mocroft et al, 2004). Similarly, there has been a downward trend in the prevalence of oral opportunistic lesions in response to the use of HAART (Franceschi et al, 2008;Patton et al, 2000;Ramírez-Amador et al, 2003;Shiboski, 2002;Yang et al, 2010). Notable reduction was reported in the prevalence of two most common HIV-associated lesions, oral candidiasis and hairy leukoplakia (Eyeson et al, 2002;Nicolatou-Galitis et al, 2004;Patton et al, 2000;Ramírez-Amador et al, 2003).…”