HIV-Related and Epstein-Barr Virus-Associated Anal Burkitt's Lymphoma: Report of a Case

Freudenberg, S.; Palma, Pablo; Grobholz, Rainer; Ngendahayo, Louis; Post, Stefan

doi:10.1007/s10350-005-0106-9

Cited by 12 publications

(2 citation statements)

References 21 publications

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“…11 EBV is often demonstrated in immunocompromised patients and is considered capable of inducing high-grade lymphoma. 11,12 Children with primary immunodeficiency, for example, Wiskott-Aldrich syndrome, are at higher risk of malignancies, and non-Hodgkin lymphoma in particular, but BL is rarely reported. 13 Rectal BL in children without acquired or congenital immunodeficiencies, such as the case described here, is a very rare event.…”

Section: Discussionmentioning

confidence: 98%

Rectal Burkitt Lymphoma in Childhood

Favini

Massimino

Esposito

et al. 2008

Journal of Pediatric Hematology/Oncology

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Lymphomas are the third most common cancer in children and Burkitt lymphoma (BL) accounts for about 40% of them. The rectum is extremely seldom involved in BL: 91 children were treated at our institution for BL between 1987 and June 2006, but none of them had involved the rectum. We report here on a 9-year-old boy who presented with bowel bleeding and subocclusion, which proved due to a BL of the rectum. The role of surgery for this tumor is limited nowadays, except for surgical emergencies, biopsies, and second-look surgery in selected cases.

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Section: Discussionmentioning

confidence: 98%

Rectal Burkitt Lymphoma in Childhood

Favini

Massimino

Esposito

et al. 2008

Journal of Pediatric Hematology/Oncology

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“…BL accounts for 1–2% of all cases of non-Hodgkin’s lymphoma (NHL). NHL of the GI tract is mostly found in the stomach (about 50–60%) and small intestine (about 30%), while the large bowel and rectum account for only 10% of all cases [ 9 ]. Primary non-Hodgkin’s lymphoma (NHL) of the rectum accounts for 0.1–0.5% of all malignant rectal tumors.…”

Section: Discussionmentioning

confidence: 99%

Burkitt’s Lymphoma of the Rectosigmoid and Stomach Presenting as Hematochezia

et al. 2016

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Patient: Female, 51Final Diagnosis: Burkitt’s lymphoma of the rectum and stomachSymptoms: HematocheziaMedication: —Clinical Procedure: EGD and colonoscopySpecialty: Gastroenterology and HepatologyObjective:Rare diseaseBackground:Burkitt’s lymphoma (BL) is an uncommon cause of non-Hodgkin lymphoma in adults and accounts for only 0.1–0.5% of all malignant tumors of the colon and rectum. Very few cases of rectosigmoid and stomach BL have been reported in adults.Case Report:A 51-year-old Hispanic woman presented with a 1-month history of hematochezia, associated with a foreign-body sensation in the rectum and 7 kg weight loss. Initial laboratory workup showed normocytic anemia and positive fecal occult blood. Computed tomography of the abdomen revealed an asymmetric appearance of the stomach and pylorus with nodularity of the mucosa and thickening of the posterior wall, and a 10.8-cm rectal mass. Esophagogastroduodenoscopy and colonoscopy were performed and biopsies of the stomach and rectum were obtained; histopathology demonstrated involvement by Burkitt’s lymphoma in the gastric body nodule and rectal mass. After 4 cycles of chemotherapy, a follow-up abdominal CT demonstrated complete resolution of the mural thickening of the rectum and no intra-abdominal lymphadenopathy.Conclusions:Our case illustrates the importance of considering BL in the extensive differential diagnosis of rectal bleeding, change in bowel habits, and other lower and upper GI symptoms, since the rapidly growing nature of this rare malignancy requires a prompt diagnosis and initiation of appropriate therapy.

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Anal lymphoma: a tumor with insufficient attention

Liu

Chen

2023

Discov Onc

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Background Anal lymphomas are extremely rare. There are no relevant descriptions in professional books, and there are only a few case reports in the literature. Here, we report a new case and review the literature to summarize the clinical and pathological features of anal lymphoma. Methods We described a case of anal lymphoma confirmed by pathological diagnosis, then searched the PubMed database, and finally selected 12 reported cases to be included in the study. We described the clinical and pathological characteristics of the patients. Results Thirteen patients with anal lymphoma were confirmed. Seven men and six women with a median age of 50. There were four cases of HIV- and EBV-infected patients. The size of the tumor was 1–13 cm, all of which were diagnosed as B-cell lymphoma, and 61.5% were diffuse large B-cell lymphomas. Among the 13 patients, eight received chemotherapy or immunochemotherapy, two received radiotherapy, one received chemotherapy combined with radiotherapy, one received surgery, and one gave up treatment. Three patients died, and only 2 of 10 surviving patients had complete remission. Conclusion Anal lymphoma is extremely rare. Patients with persistent abscess complicated with HIV or EBV infection should undergo pathological biopsy to exclude anal lymphoma.

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HIV-Related and Epstein-Barr Virus-Associated Anal Burkitt's Lymphoma: Report of a Case

Abstract: Because of the AIDS epidemic and the increase of anal malignant pathologies, anal Burkitt's lymphoma may appear more frequently. Adequate treatment is available for only a small percentage of patients.

Cited by 12 publications

References 21 publications

Rectal Burkitt Lymphoma in Childhood

Rectal Burkitt Lymphoma in Childhood

Burkitt’s Lymphoma of the Rectosigmoid and Stomach Presenting as Hematochezia

Anal lymphoma: a tumor with insufficient attention

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