HIV infection in the west region of Pará

Abstract

Aims: knowledge of the patient’s profile, for the evaluation and suggested behaviors, promotes a favorable outcome. Thus, the objective of the study is to analyze the socioeconomic, clinical, and immunological characteristics of patients infected by the human immunodeficiency virus in the western region of the state of Pará.Methods: were analyzed 1966 medical records of patients whose first visit to a reference center, in the municipality of Santarém-PA, was between 1998 and 2018. Socioeconomic, clinical, and immunological information was collected from patient medical records. Data were analyzed using descriptive and inferential statistics, adopting p <0.05.Results: there was a predominance of males (62.5%), aged 20-39 years (69.1%), elementary school (58.6%), single (57.3%), and employed (66.4%). Immunosuppression was present in 22% of patients and a viral load was detectable in 66%. Tuberculosis (37%) and toxoplasmosis (23%) predominated as opportunistic infections, and syphilis (62.6%) and human papillomavirus (HPV; 14%) as other infections.Conclusions: it is concluded that both opportunistic infections and other infections were present in 25-22% of the patients and that the presence of opportunistic infections favors the installation of another infection, or vice versa. Toxoplasmosis, HPV, and syphilis are positively associated with men, and toxoplasmosis and tuberculosis with age >35 years. Immunosuppression was shown to be positively associated with men and age >35 years, as well as favoring the onset of tuberculosis, toxoplasmosis, and detectable viral load.

Sífilis em pessoas vivendo com HIV acompanhados em hospital de referência no Brasil entre 2015 e 2020.

“…Estudos denotando a coinfecção por sífilis e HIV são frequentes na literatura, entretanto, a maior parte se concentra em estudar pacientes com diagnóstico pelo HIV e avaliar a prevalência da coinfecção por sífilis 10,11,[17][18][19] . Um estudo turco demonstrou que cerca de 12% dos pacientes com infecção pelo HIV-1 haviam sido expostos ao T. pallidum, ao passo que cerca de 1% desenvolveu testes não treponêmicos compatíveis com a sífilis 17 .…”

“…A coinfecção por sífilis em pessoas vivendo com HIV tem sido descrita também em outras unidades federativas. Um estudo de corte transverso realizado no CTA e ambulatório de IST no Pará, com pessoas vivendo com HIV atendidas entre 1998 e 2018, descreveu uma coinfecção por sífilis em 14,1% dos pacientes 10 . Em Goiás, um estudo transversal realizado em 2018, também com pessoas vivendo com HIV, descreveu um predomínio de coinfecção por sífilis de 76,8% 11 .…”