“…Six of them, all from the U.S., predated the introduction of highly active ART in 1996, 31,48e52 and five were conducted in the era of ART. 22,25,32,53,54 Pain (11 Studies) Table 2 displays the findings in the domains of pain and physical problems, by population group. In prospective observational studies, pain prevalence ranged from 31% to 53% in middle-income country outpatient populations, 46,55 and was 76% among low-income country patients with AIDS 41 and 69% for inpatients with herpes zoster.…”