HIV epidemiology, prevention, treatment, and implementation strategies for public health

Mody, Aaloke; Sohn, Annette H; Iwuji, Collins; Tan, Rayner K J; Venter, Francois; Geng, Elvin H

doi:10.1016/s0140-6736(23)01381-8

The Lancet

2024

DOI: 10.1016/s0140-6736(23)01381-8

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HIV epidemiology, prevention, treatment, and implementation strategies for public health

Aaloke Mody,

Annette H Sohn,

Collins Iwuji

et al.

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2024

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The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

Lee,

Oh,

Park

et al. 2024

Preprint

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This systematic review and meta-analysis aimed to investigate the prevalence of self-reported sleep disturbances in people living with HIV considering the effects of age, depression, anxiety, CD4 cell counts, time since HIV diagnosis, study region, and the instruments used to measure sleep disturbances. We searched PubMed, PsycINFO, and EMBASE to include eligible articles. In this meta-analysis of 43 studies, the pooled prevalence of self-reported sleep disturbances was 52.29% (95% confidence interval = 47.69–56.87). The subgroup analyses revealed that variations in the sleep measurements and study region significantly contributed to the observed heterogeneity. In the meta-regression analyses, higher proportions of participants with depression or anxiety and longer times since HIV diagnosis were significantly associated with a higher prevalence of self-reported sleep disturbances after adjusting for mean age. Our findings emphasise the substantial burden of sleep disturbances in people living with HIV and identified comorbid depression and anxiety and the time since HIV diagnosis as significant moderators. These results underscore the importance of considering these factors when designing tailored screening programmes for high-risk patients and implementing early interventions to prevent and mitigate sleep disturbances in people living with HIV.

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The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

Lee,

Oh,

Park

et al. 2024

Preprint

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HIV epidemiology, prevention, treatment, and implementation strategies for public health

Cited by 1 publication

References 274 publications

The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

The prevalence and moderating factors of sleep disturbances in people living with HIV: A systematic review and meta-analysis

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