HIV Counseling and Testing in an Urban Reproductive Primary Health Clinic in South Africa

Ramkissoon, Arthi; Beksinska, Mags; Searle, Catherine; Govender, Thamandrie; Smit, Jenni; Kleinschmidt, Immo

doi:10.1097/qai.0b013e3182381171

Cited by 2 publications

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“…Poor prognostic markers of ART response were apparent in men at baseline, who were older, had lower CD4+ cell counts and higher viral loads compared to women. This finding concurs with published South African literature demonstrating that compared to men, women were more likely to access HIV testing, and among those testing HIV positive, women were younger with higher CD4+ cell counts than their male counterparts [ 27 ].…”

Section: Discussionsupporting

confidence: 91%

“…This study also showed that the late presentation of men was associated with poor immunological response to ART with higher risk of morbidity and mortality [ 27 ]. Our findings of significant correlation between baseline characteristics, virological suppression rates, immunologic recovery and mortality concur with previously published studies conducted in South Africa [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

“…Adverse clinical outcomes notably death can be masked by LTFU resulting in the underestimation of actual mortality rates within ART programmes [ 35 ]. Previous South African studies have documented gender differences in service uptake within the HIV care cascade; women have higher rates of HIV testing [ 27 ] and linkage to care than men [ 13 ]. Once initiated on ART, men have poorer adherence [ 36 ] and lower retention in care [ 28 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

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High mortality rates in men initiated on anti-retroviral treatment in KwaZulu-Natal, South Africa

et al. 2017

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In attaining UNAIDS targets of 90-90-90 to achieve epidemic control, understanding who the current utilizers of HIV treatment services are will inform efforts aimed at reaching those not being reached. A retrospective chart review of CAPRISA AIDS Treatment Program (CAT) patients between 2004 and 2013 was undertaken. Of the 4043 HIV-infected patients initiated on ART, 2586 (64.0%) were women. At ART initiation, men, compared to women, had significantly lower median CD4+ cell counts (113 vs 131 cells/mm3, p <0.001), lower median body mass index (BMI) (21.0 vs 24.2 kg/m2, p<0.001), higher mean log viral load (5.0 vs 4.9 copies/ml, p<0.001) and were significantly older (median age: 35 vs. 32 years, p<0.001). Men had higher mortality rates compared to women, 6.7 per 100 person-years (p-y), (95% CI: 5.8–7.8) vs. 4.4 per 100 p-y, (95% CI: 3.8–5.0); mortality rate ratio: 1.54, (95% CI: 1.27–1.87), p <0.001. Age-standardised mortality rate was 7.9 per 100 p-y (95% CI: 4.1–11.7) for men and 5.7 per 100 p-y (95% CI: 2.7 to 8.6) for women (standardised mortality ratio: 1.38 (1.15 to 1.70)). Mean CD4+ cell count increases post-ART initiation were lower in men at all follow-up time points. Men presented later in the course of their HIV disease for ART initiation with more advanced disease and experienced a higher mortality rate compared to women.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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High mortality rates in men initiated on anti-retroviral treatment in KwaZulu-Natal, South Africa

et al. 2017

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“…Men are less likely to test for HIV than women in many African countries (Venkatesh et al 2011;Ramkissoon et al 2011;Shisana et al 2009;Mills et al 2012;Angotti et al 2009). In Kenya in 2012, 35.8% of men versus 47.3% of women had been tested for HIV in the past year (UNAIDS 2014a).…”

Section: Introductionmentioning

confidence: 99%

Evaluating oral HIV self-testing to increase HIV testing uptake among truck drivers in Kenya

Kelvin¹,

Mwai²,

Romo³

et al. 2017

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The International Initiative for Impact Evaluation (3ie) is an international grant-making non-governmental organization promoting evidence-informed development policies and programs. We are the global leader in funding, producing and synthesizing high-quality evidence of what works, for whom, why and at what cost. We believe that high-quality and policy-relevant evidence will help make development more effective and improve people's lives. 3ie impact evaluations3ie-supported impact evaluations assess the difference a development intervention has made to social and economic outcomes. 3ie is committed to funding rigorous evaluations that include a theory-based design, and use the most appropriate mix of methods to capture outcomes that are useful in complex developmental contexts.

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HIV Counseling and Testing in an Urban Reproductive Primary Health Clinic in South Africa

Cited by 2 publications

References 0 publications

High mortality rates in men initiated on anti-retroviral treatment in KwaZulu-Natal, South Africa

High mortality rates in men initiated on anti-retroviral treatment in KwaZulu-Natal, South Africa

Evaluating oral HIV self-testing to increase HIV testing uptake among truck drivers in Kenya

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