HIV and Malaria Co infection in the Department of Paediatrics of the University Teaching Hospital Souro Sanou

Abstract

Corresponding author: Ouédraogo S Macaire, Doctor internist to the University hospital Souro Sanou, Department of internal medicine, immunology and hematology Mail box 676, Teaching Higher institute of the health sciences Abstract Introduction: Malaria and HIV are the leading causes of mortality and morbidity in sub-Saharan Africa. The interaction of these two pathologies raises fundamental as well as therapeutic issues. This study seeks a better understanding of the clinical profile of coinfected biological and therapeutic HIV-Malaria in Children's at Hopital Pédiatrique du jour of Centre Hospitalier Universitaire Souro SANOU (CHUSS), Bobo-Dioulasso.Methodology: It is a cross-sectional study with prospective and retrospective aspects. Included, were patients infected with HIV and followed in the department who's clinical and laboratory diagnosis of malaria had been performed and/or patients with whom the diagnosis of co-infection was done at the occasion of a medical consultation following the consent of the legal representative. Results:The prevalence of coinfection was 3.09%. The clinical signs of severity were dominated by impaired consciousness, convulsions and dehydration. As for biological signs, anemia was found in 65% of patients; leukocytosis was found in 19.6% of coinfected and thrombocytopenia in 9.3% of cases. HIV-1 was the most encountered stereotype and immunocompetent patients accounted for 70.7% of coinfected. Pharmaco therapeutic groups were mainly administered antimalarial (100% of cases), analgesics-antipyretics (79.6% of cases), ART (48.1% of cases), antibiotics, especially cotrimoxazole (21.3% cases). Conclusion:Immunosuppression induced by HIV infection did not appear to be associated with the frequency of occurrence of malaria. Chemo malaria prophylaxis in children living with HIV is not necessary. Consequently, malaria as a reason for consultation could be a gateway for the recruitment of children infected with HIV.