HIV/AIDS and Antiretroviral Treatment Knowledge, Attitudes, Beliefs, and Practices in HIV-Infected Adults in Soweto, South Africa

Nachega, Jean B.; Lehman, Dara A.; Hlatshwayo, Dorothy; Mothopeng, R.; Chaisson, Richard E.; Karstaedt, Alan

doi:10.1097/00126334-200502010-00011

Cited by 105 publications

(114 citation statements)

References 9 publications

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“…Importantly, more than half of these patients reported to know the AEs associated with their particular medicines and also what to do in the event of AEs. A study conducted in South Africa showed good knowledge of ART [11] but this sharply contrasted with findings by other investigators which reported poor knowledge [9,17]. The study designs were similar to what was employed in this study as knowledge was based on "patients self-report" events.…”

Section: Discussioncontrasting

confidence: 68%

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Knowledge and Attitudes of HIV Infected Patients on the Adverse Effects of Antiretroviral Medicines in Ghana

Tetteh¹,

Nartey²,

Lartey³

et al. 2017

J Pharmacovigil

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Antiretroviral Therapy (ART) is effective in reducing morbidity and mortality in patients living with HIV/AIDS (PLWHA). However, Adverse Effects (AEs) to ART pose major problems and threaten adherence to therapy. We evaluated the knowledge and attitudes of patients to ART following routine adherence counselling and education in the Korle Bu Teaching Hospital in Accra, Ghana. This cross-sectional study was conducted by administering a questionnaire on socio-demographics, knowledge of AEs of antiretrovirals and attitude to AEs to 98 patients who were on antiretroviral therapy. A 3-point Likert-scale was used to assess knowledge of AEs of ART and a 5 point Likert-scale to assess attitudes to AEs. Mean rated scores for attitude to AEs were estimated and factor analysis was used to reduce the dimensions of the attitudes observed to identify relevant latent constructs. Sixty one percent of participants were females and most of the participants were aged 35-44 years (35%). Ninety nine percent of participants answered that they had been counselled on unpleasant effects of their medicines and 93% knew that all medicines could cause some unpleasant effects. Concerning attitude, 90% of study participants strongly agreed that they benefit from their medicines and get better taking them (mean rated score=4.87 ± 0.49) whilst 27% strongly agreed that medicines may have side effects (mean rated score=3.12 ± 1.55). Majority of the study participants (74%) strongly disagreed that there was no need to tell their doctor/pharmacist about AEs to antiretrovirals (mean rated score=4.60 ± 0.83). Factor analysis yielded two underlying dimensions (cognitive and behavioural/affective aspects) that described participants' attitude towards AEs. Study participants rating for participants' knowledge on AEs was good and exhibited positive attitudes to AEs of ART. Adherence counselling and education provided to PLWHA before initiation of antiretroviral therapy is beneficial and should be continued.

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Section: Discussioncontrasting

confidence: 68%

“…Knowledge is defined as facts, information, and skills acquired through experience or education; the theoretical or practical understanding of a subject [11]. A study conducted in Gabon [12], concluded that patients want to be provided the complete drug information including the side effects and any difficulties that could be experienced.…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Attitudes of HIV Infected Patients on the Adverse Effects of Antiretroviral Medicines in Ghana

Tetteh¹,

Nartey²,

Lartey³

et al. 2017

J Pharmacovigil

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“…HIV positive women with formal education were significantly almost two times more likely to have a comprehensive knowledge on PMTCT and A RT (OR=1.9; p=0.003). Negative perceptions about ART were associated with low education level in the study by [12]. The wo men whose husbands had formal education were also more likely to have comprehensive knowledge on PMTCT and ART as compared to those this no formal education (78% vrs 73%; OR = 0.23).…”

Section: Knowledge On Pmtctmentioning

confidence: 74%

“…The respondents who have achieved optimal access cited the need to adhere to ensure effectiveness of the drug as a reason for always coming for ART appointment. Overall, knowledge of the cause of HIV/AIDS, modes of transmission, and importance of ART adherence was good in a study in South Africa [12].…”

Section: Art Defaul Ting Ratementioning

confidence: 97%

Knowledge, Perceptions and Practices on Antiretroviral Therapy in Farming Communities in Ghana: A Study of HIV Positive Women

Boateng¹,

Awunyo‐Vitor²

2012

PHR

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Low levels of knowledge of antiretroviral therapy (ART) and Prevention of Mother-To-Child-Trans mission (MTCT) among persons living with HIV present an unwanted window for transmission within the general population. The purpose of this study is to assess the level of knowledge, attitudes and perceptions of HIV positive wo men on antiretroviral therapy (ART) and Prevention of Mother-To-Ch ild-Transmission (MTCT). The study surveyed 211 HIV positive wo men fro m A RT centres in two districts in Ashanti region of Ghana. Data was collected through interviews using structured questionnaires and focus group discussion using interview guides. Qualitative and quantitative techniques were used to analyze the data. The study revealed that about 15% of the wo men exh ibited no knowledge about the possibility of transmission of HIV fro m mother to child whilst 36% had no knowledge on the mode of MTCT of HIV. Those who had knowledge of MTCT indicated that this could be intrauterine (88%), delivery (69%) and through breastfeeding (82 %).Mothers with inco mprehensive knowledge on ART were 2.5 t imes more likely to defau lt A RT (OR=2.5, p=0.002). Co mprehensive knowledge was positively influenced by high education level (OR=1.9; p =0.003). Social marketing campaigns should be developed and targeted at improving wo men literacy on their health issues and getting more wo men to test for HIV in order to incorporate them into PMTCT programmes. Further research however needs to be conducted to ascertain the facility and community based factors that influence the women's knowledge on ART and PMTCT.

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“…HIV transmission risk in patients on HAART is low only if the following conditions are met: the HIV-infected patient is receiving HAART with excellent adherence; patients disclose their HIV status and inquire about HIV status of their sexual partners; the viral load is consistently undetectable for a long time; and no sexually transmitted infections (STIs) are present in either partners. The above conditions are not met in many sub-Saharan African settings, as many studies [56][57][58][59][60][61] report that sub-optimal adherence, high fertility intentions, and risk factors for acquisition of STI (such as multiple sexual partners, and inconsistent condom use) are common. In many settings in sub-Saharan Africa, such as eastern and southern Africa, high-risk behaviors occur in HIV patients before and after initiating HAART [62][63][64][65].…”

Section: Discussionmentioning

confidence: 99%

The impact of highly active antiretroviral therapy on high-risk behaviour of HIV-infected patients in sub-Saharan Africa

Kaye

Kakaire

Osinde

et al. 2013

J Infect Dev Ctries

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Introduction: High-risk sexual behaviors such as multiple sexual partners, inconsistent condom use, acquisition of sexually transmitted infection (STIs), and non-use of contraceptives persist in HIV patients undergoing care. We conducted a systematic review of studies conducted in the era of increased access to HAART (2000HAART ( -2010 to assess whether wide-scale use of HAART was associated with high-risk behavior among HAART-using patients. Methodology: We conducted a comprehensive search of databases (AIDSLINE, National Library of Medicine, MEDLINE, PubMed, CINHAL and EMBASE) from January 2002 to January 2010, reviewed conference proceedings and journals, and contacted the researchers involved. We analyzed the association of high-risk behaviors (non-disclosure of sero-status to sexual partners, inconsistent condom use, unprotected sexual intercourse, multiple sexual partners, non-use of contraceptives and acquisition of STIs) with using HAART. Information from eligible studies was abstracted using a standardized checklist. Fourteen English-language studies met the selection criteria of having high-risk behavior as an outcome in patients using HAART in sub-Saharan Africa. Results: Of the 92 eligible articles screened, 14 met the criteria for inclusion as primary articles, 10 showed that HAART is not associated with increased high-risk behavior, two showed increase in acquisition of STIs among HAART-using patients, (which was inconsistent with other measures of high-risk behavior), and two studies showed short-term increase in high-risk behavior. Conclusions: Persistence of high-risk behavior in HAART-using patients suggests that more effort needs to be incorporated in HIV care to reduce such behavior to reduce HIV transmission to uninfected populations.

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HIV/AIDS and Antiretroviral Treatment Knowledge, Attitudes, Beliefs, and Practices in HIV-Infected Adults in Soweto, South Africa

Cited by 105 publications

References 9 publications

Knowledge and Attitudes of HIV Infected Patients on the Adverse Effects of Antiretroviral Medicines in Ghana

Knowledge and Attitudes of HIV Infected Patients on the Adverse Effects of Antiretroviral Medicines in Ghana

Knowledge, Perceptions and Practices on Antiretroviral Therapy in Farming Communities in Ghana: A Study of HIV Positive Women

The impact of highly active antiretroviral therapy on high-risk behaviour of HIV-infected patients in sub-Saharan Africa

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