“…Hepatitis E was believed to countries, primarily in Asia (range: min 8.1% China [Shenyang et al, 2011] and max 22.5% Bangladesh [Labrique et al, 2010]) and Africa (range: min 4.3% Tunisia [Rezig et al, 2008] and max 79.5% Bangui [Goumba et al, 2011]); but also in some regions of Eastern Europe there is a high rate of HEV infection (Hungary 9.6% [Reuter et al, 2009] and Romania 12.5% [Voiculescu et al, 2010]). HEV appears to be the second most frequent cause of enterically transmitted disease after hepatitis A virus (HAV) [Schmid, 2001]; in high‐endemic areas, HEV infection accounts for a large proportion of acute sporadic hepatitis in all age groups [Vishwanathan, 1957]. In our study, it was observed a high‐rate of HEV infection in a cohort of immigrants who had just arrived (<2 months) in Italy, as already showed by previous studies on immigrants arriving from developing countries to our land [De Donno et al, 2003].…”