This article deals with the genocide against the Rohingya Muslims in Myanmar. For decades, the Rohingya in Myanmar has been the victim of the extensive violation of human rights. Recently the Rohingya, Karen, San, Chin, and other ethnic groups are facing ethnic cleansing in Myanmar. Of them, the Rohingya is the mostly dehumanized and persecuted ethnic minority group. The Rohingya is stateless and exile in its own country. The Government of Myanmar (GoM) has taken attempts for establishing one nation, one language, and one religious policy in the country. Since 2012 the persecution upon the Rohingya in Myanmar falls in the genocide. In 1917, the Rohingya faced the final stages of genocide. Genocide is considered as one of the worst moral crimes a Government can commit against its citizens. An attempt has been taken here to discuss the aspects of genocide, and genocide upon the Rohingya Muslims in Myanmar.