History of Post‐Polymerization Modification

Poly(bromoethyl acrylate): A Reactive Precursor for the Synthesis of Functional RAFT Materials

“…[47][48][49][50][51][52] However, thio-bromo substitutions have not been thoroughly explored for main chain functionalization of polymers by controlled radical polymerization. (1), and post-substitution pTPEA 50 , showing the similarity in distribution (B) 1 H NMR in DMSO-d 6 indicating the shifts of the pendant ethyl acrylate chain for protons α and β of pBEA 50 (1) and protons α' and β' of pTPEA 50 .…”

“…[1][2][3][4][5] However, inclusion of desirable material properties, in addition to well-controlled polymerization is limited by the range of chemical functionalities accessible to these polymerization techniques. [6][7][8] In light of this, post-modification of a reactive polymer precursor provides an attractive approach to overcoming this limitation, enabling synthesis of diversely functional materials, without subjecting them to detrimental polymerization conditions. [9][10][11][12][13] A variety of post-polymerization methods have previously been explored, [6][7][8][9] including copper-catalysed azide/alkyne click (CuAAC), [14][15][16] Diels-Alder cycloadditions [17][18][19][20] and active ester couplings.…”

“…[6][7][8] In light of this, post-modification of a reactive polymer precursor provides an attractive approach to overcoming this limitation, enabling synthesis of diversely functional materials, without subjecting them to detrimental polymerization conditions. [9][10][11][12][13] A variety of post-polymerization methods have previously been explored, [6][7][8][9] including copper-catalysed azide/alkyne click (CuAAC), [14][15][16] Diels-Alder cycloadditions [17][18][19][20] and active ester couplings. 10,[21][22][23] These methods enable the introduction of complex functional groups targeting applications ranging from drug delivery to organic electronics.…”

Poly(2-oxazoline)s and click chemistry: A versatile toolbox toward multi-functional polymers

“…to the polymer backbone is preferably performed via post-polymerization modification reactions. 31 In order to retain the highly defined structure in the final (co)polymer, the number of post-polymerization reaction steps should be minimized and highly selective reactions with quantitative conversion are of utmost importance. The concept of click chemistry, therefore, perfectly matches this need for straightforward, efficient postpolymerization modification of PAOx (co)polymers that are intended for biomedical use.…”

Synthesis of Novel Nitroxide Radical Polymer Materials for Imaging and Energy Storage Applications

“…[238][239][240][241] This alternative synthetic route to the ones discussed in the previous chapters is particularly attractive for the preparation of the notoriously challenging to synthesize radical polymers. This strategy allows for two key advantages that would otherwise be impeded by the presence of the paramagnetic nitroxides: (a) utilization of the full toolbox of radical polymerization techniques and (b) structural elucidation of the macromolecular precursor architecture via NMR.…”