2011
DOI: 10.1111/j.1460-9592.2011.03636.x
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History of pediatric regional anesthesia

Abstract: The history of local and regional anesthesia began with the discovery of the local anesthetic properties of cocaine in 1884. Shortly afterwards nerve blocks were being attempted for surgical anesthesia. Bier introduced spinal anesthesia in 1898, two of his first six patients being children. Spinal anesthesia became more widely used with the advent of better local anesthetics, stovaine and procaine in 1904-1905. Caudals and epidurals came into use in children much later. In the early years these blocks were per… Show more

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Cited by 46 publications
(24 citation statements)
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“…The new interest for the use of spinal anesthesia rose three decades ago when awake spinal anesthesia was introduced for herniotomies in preterm neonates with high risk of apnea associated with general anesthesia (2). However, spinal anesthesia is a feasible technique not only in neonates but also in older children and adolescents (3).…”
Section: Introductionmentioning
confidence: 99%
“…The new interest for the use of spinal anesthesia rose three decades ago when awake spinal anesthesia was introduced for herniotomies in preterm neonates with high risk of apnea associated with general anesthesia (2). However, spinal anesthesia is a feasible technique not only in neonates but also in older children and adolescents (3).…”
Section: Introductionmentioning
confidence: 99%
“…The caudal technique is extensively described by Key in 1994. 5 When regional anesthesia is given to older children, some variables such as the intervention site, age, and presence of chronic disease, cooperativeness and parental preferences should be considered. In present study we compared caudal block with spinal block in pediatric patients.…”
Section: Introductionmentioning
confidence: 99%
“…9 Although the first successful spinal anesthesia was performed in an 11-year old by August Bier in 1898, 10 and the first caudal anesthesia was performed in 1933, 11 in the mid-20th century, US doctors rarely performed regional anesthesia in children. 12 Working initially in a cadaver laboratory to determine the doses of local anesthetic needed to achieve satisfactory dermatomal spread, and then with children in IRB-approved research trials, Melman et al 9,13 was among the first to demonstrate the effectiveness of neural blockade, particularly the caudal approach to the epidural space, in pediatric anesthesia. Indeed, her original study was met with substantial skepticism and was rejected by one of the editors at Anesthesia and Analgesia.…”
mentioning
confidence: 99%