Historical inability to control Aedes aegypti as a main contributor of fast dispersal of chikungunya outbreaks in Latin America

Fernández‐Salas, Ildefonso; Danis‐Lozano, Rogelio; Casas-Martínez, Mauricio; Ulloa, Armando; Bond, J. Guillermo; Marina, Carlos F.; López‐Ordóñez, Teresa; Elizondo-Quiroga, Armando; Torres-Monzón, Jorge Aurelio; Díaz-González, Esteban E.

doi:10.1016/j.antiviral.2015.10.015

Cited by 64 publications

(51 citation statements)

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“…Considering the ongoing CHIKF outbreak, which followed a similar pathway to the Americas in 2013, followed by an epidemic of hemispheric proportions [36], as well as our inability to control DENV in the Americas for many decades, the prospects for controlling or slowing the spread of ZIKV are poor. Nevertheless, source reduction and insecticide-based control inside and around homes, schools, and places of work should be redoubled and supplemented by more-recently developed methods, such as lethal traps, until transgenic and Wolbachia-based methods can be scaled-up for use in large populations [37]. Fortunately, the majority of ZIKF cases are mild or unapparent, and the overall global disease burden is smaller than that of CHIKV and DENV.…”

Section: Discussionmentioning

confidence: 99%

Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission byAedes aegyptiMosquitoes in the Americas

et al. 2016

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Background. After decades of obscurity, Zika virus (ZIKV) has spread through the Americas since 2015 accompanied by congenital microcephaly and Guillain-Barré syndrome. Although these epidemics presumably involve transmission by Aedes aegypti, no direct evidence of vector involvement has been reported, prompting speculation that other mosquitoes such as Culex quinquefasciatus could be involved.Methods. We detected an outbreak of ZIKV infection in southern Mexico in late 2015. Sera from suspected ZIKV-infected patients were analyzed for viral RNA and antibodies. Mosquitoes were collected in and around patient homes and tested for ZIKV.Results. Of 119 suspected ZIKV-infected patients, 25 (21%) were confirmed by RT-PCR of serum collected 1-8 days after the onset of signs and symptoms including rash, arthralgia, headache, pruritus, myalgia, and fever. Of 796 mosquitoes collected, A. aegypti yielded ZIKV detection by RT-PCR in 15 of 55 pools (27.3%). No ZIKV was detected in C. quinquefasciatus. ZIKV sequences derived from sera and mosquitoes showed a monophyletic relationship suggestive of a point source introduction from Guatemala.Conclusions. These results demonstrate the continued, rapid northward progression of ZIKV into North America with typically mild disease manifestations, and implicate A. aegypti for the first time as a principal vector in North America.

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Section: Discussionmentioning

confidence: 99%

Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission byAedes aegyptiMosquitoes in the Americas

et al. 2016

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“…Other problems derived from this situation are that most of the surveillance systems are based on passive detection of suspected cases (some without a correct diagnosis), cases without warning signs are generally sent back to their homes with just symptomatic medicinal treatment [24], and a lack of notification to the surveillance system. The case notification system is closely related to vector-control activities [4] and without an alert for a high number of cases, there is no vector-control intervention in the communities.…”

Section: Discussionmentioning

confidence: 99%

“…Aedes aegypti is one of the most important vectors of viruses, transmitting diseases such as dengue, chikungunya, zika, yellow fever, and more recently, mayaro virus. High infestation rates of this mosquito are responsible for maintaining these arbovirus outbreaks in endemic areas, such as Colombia [4].…”

Section: Introductionmentioning

confidence: 99%

Knowledge, Attitudes and Practices Regarding Dengue, Chikungunya, and Zika and their Vector Aedes Aegypti in Villavicencio, Colombia

Jaramillo¹,

Álvarez²

2017

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“…Israelensis. 54,81 La falla de los actuales métodos ha llevado al desarrollo de nuevas estrategias como las téc-nicas de insectos estériles (SIT, por sus siglas en inglés) que se han incrementado en los últimos años y la más importante es la de los mosquitos irradiados y transgénicos, ambas técnicas basadas en la liberación de machos estériles que copulan con hembras salvajes, produciendo descendencia infértil. Además de éstas se encuentran las técnicas de insectos incompatibles (IIT) que usa la bacteria Wolbachia para producir incompatibilidad citoplasmática en mosquitos Aedes.…”

Section: Innovaciones En Control De Vectoresunclassified

Arbovirus en Latinoamérica

2016

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ResumenLas enfermedades producidas por arbovirus son un problema muy grave a nivel mundial, debido a que su vigilancia y prevención implica también la vigilancia de sus vectores, lo que hace difícil su control y casi imposible evitar su expansión a cualquier país tropical o subtropical, e incluso algunas regiones templadas. A nivel mundial, el dengue es la enfermedad por arbovirus más común con 40% de la población mundial viviendo en zonas de transmisión del virus del dengue. De las 390 millones de infecciones estimadas y 100 millones de casos anuales, una proporción pequeña de estos casos progresa a dengue grave. Aproximadamente uno de cada 2,000 casos de dengue causan la muerte; sin embargo, la tasa de letalidad de los pacientes con dengue grave se puede reducir de casi 10% a menos del 0.1% si se actúa rápidamente y con calidad en la atención clínica que reciben los pacientes. Esto, aunado a la reciente y rápida propagación del virus chikungunya y el brote de virus zika en países latinoamericanos, como México, hace necesaria la actualización médica y revisión de bibliografía respecto a la prevención, control y gestión de las infecciones causadas por arbovirus. Por lo tanto, presentamos una revisión de lo más reciente sobre enfermedades por arbovirus en América Latina. Arbovirus in Latin AmericaAbstract Diseases produced by arboviruses are a major worldwide problem due to the fact that the surveillance and prevention of them implies the surveillance of vectors, which makes it very difficult to control them, and almost impossible to avoid their expansion to any tropical or subtropical country, and even some temperate regions. Globally, dengue is the most common arboviral disease, with 40% of the world population living in areas with dengue virus transmission. Of the estimated 390 million infections and 100 million cases annually, a small proportion of these cases progress to severe dengue. Approximately one in 2,000 dengue cases result in death. However, the case-fatality rate of patients with severe dengue can be reduced from almost 10% to less than 0.1% by the timing and quality of clinical care that patients receive. This, coupled with the recent and quick spread of Chikungunya virus and the outbreak of Zika virus in Latin American countries including Mexico, makes it necessary the medical update and review of bibliography concerning the prevention, control and management of arboviral-caused diseases. Therefore we present a review of the most recent literature on arboviral diseases in Latin America.

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Historical inability to control Aedes aegypti as a main contributor of fast dispersal of chikungunya outbreaks in Latin America

Cited by 64 publications

References 102 publications

Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission byAedes aegyptiMosquitoes in the Americas

Outbreak of Zika Virus Infection, Chiapas State, Mexico, 2015, and First Confirmed Transmission byAedes aegyptiMosquitoes in the Americas

Knowledge, Attitudes and Practices Regarding Dengue, Chikungunya, and Zika and their Vector Aedes Aegypti in Villavicencio, Colombia

Arbovirus en Latinoamérica

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