Historical evolution of regulatory standards for occupational and consumer exposures to industrial talc

Barlow, Christy A.; Bare, Jennifer L.; Jacobs, Neva; Henshaw, John L.

doi:10.1016/j.yrtph.2017.12.005

Cited by 14 publications

(8 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, Vermont talc miners and millers encountered talcs “free of both asbestiform mineral and significant quantities of free silica” ( 54 , 56 ). Some of the mines in upstate New York were reported to produce talcs with asbestiform or non-asbestiform amphibole minerals including tremolite and anthophyllite ( 42 , 43 , 57 ). Historical occupational talc exposure most often was estimated using duration of employment as a surrogate.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc

Lynch

Lauer

Thompson

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

We conducted a systematic review to assess the potential pulmonary carcinogenicity of inhaled talc in humans. Our systematic review methods adhere to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and incorporated aspects from the US Institute of Medicine (IOM) and several United States (US) Environmental Protection Agency (EPA) frameworks for systematic reviews. A comprehensive literature search was conducted. Detailed data abstraction and study quality evaluation, adapting the US Toxic Substances Control Act (TSCA) framework, were central to our analysis. The literature search and selection process identified 23 primary studies that assessed exposure to talc and pulmonary cancer risks in humans (n = 19) and animals (n = 3). Integrating all streams of evidence according to the IOM framework yielded classifications of suggestive evidence of no association between inhaled talc and lung cancer and pleural mesothelioma at human-relevant exposure levels.

show abstract

Section: Resultsmentioning

confidence: 99%

Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc

Lynch

Lauer

Thompson

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

show abstract

“…32 Talc used for cosmetic purposes has been taken from mines with higher purity (>95-99 percent) platy talc, free of other minerals, whereas industrial-grade talcs usually contain 75-95% or lower of the talc mineral with other non-platy components. 33 Talc is found in geologic fault lines and is often contaminated with the amphibole asbestos types tremolite, anthophyllite and the serpentine asbestos type chrysotile. 4,7 The asbestos fibers are more often found in the talc mines used for industrial talc as compared to the cosmetic talc mines.…”

Section: Mesotheliomamentioning

confidence: 99%

“…4,7 The asbestos fibers are more often found in the talc mines used for industrial talc as compared to the cosmetic talc mines. 33 Van Gosen et al 30 of the U.S. Geologic Survey found that many American talc deposits, including Gouverneur, New York, Vermont, and others, contain amphibole asbestos such as tremolite and anthophyllite. In the laboratory, talc has been shown to be contaminated with chrysotile, tremolite, and anthophyllite fibers.…”

Section: Mesotheliomamentioning

confidence: 99%

Asbestos in Talc and Mesothelioma: Review of the Causality Using Epidemiology

Kanarek

Liegel

2020

MRAJ

View full text Add to dashboard Cite

Talcum powder has long been contaminated with asbestos fibers depending on the source of the talc. Pleural and peritoneal mesothelioma are scientifically established as caused by asbestos exposures. However, when investigating causality of mesothelioma from asbestos fibers in talcum powder, epidemiology is complicated by various methodological issues and inadequacies in existing studies. The occupational and case studies are explored in an effort to bring clarity to the issue of talcum powder usage and mesothelioma. Talc is randomly and sporadically contaminated with asbestos fibers including chrysotile, tremolite and anthophyllite. Case studies of mesothelioma victims whose only asbestos exposure was to talc, found anthophyllite, tremolite and chrysotile asbestos fibers in their tissues. Exposure to all three types of asbestos fibers increases the risk of mesothelioma. The Hill criteria of causality, which considers all aspects of toxicology, biology and epidemiology, are applied to the issue. This analysis results in compelling evidence that asbestos in talcum powder is causative for mesothelioma. Thus, precaution would dictate the avoidance of the use of talcum powders.

show abstract

“…Regulations on workplace standards have changed since the beginning of the century in order to offer safer and healthier work environments for employees [ 21 , 22 ]. According to the European Parliament, improving health and safety at work has been an important issue for the European Union since the 1980s [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980

Miguet

Rukh

Titova

et al. 2020

IJERPH

View full text Add to dashboard Cite

Improving health and safety at work has been an important issue for the European Union since the 1980s. The existing literature supports that shift work is associated with multiple indicators of poor health but frequently neglects the potential impact of occupational hazards. This study aims at describing and comparing the exposure to different workplace hazards among shift and other workers before and after 1980. Exposure to different workplace hazards (noise, dust, pollutant, and other physical stressors) were analyzed among 119,413 participants from the UK Biobank cohort. After stratifying the analyses before and after 1980, exposure was compared between shift and other workers. Potential confounding variables (sex, age, ethnicity, education level, occupational category, and neuroticism) were adjusted for in the log-binomial regression. Shift workers had a higher prevalence ratio (PR) than other workers of being exposed to almost all identified hazards both before or after 1980. They were also more likely to be exposed to multiple hazards compared to other workers, both before 1980 (PR: 1.25; 95% CI: 1.21–1.30) and after 1980 (PR: 1.34; 95% CI: 1.30–1.38). The prevalence of all measured risk factors was higher after 1980 than before 1980 among shift workers. Of note, the work environment has improved overall for other workers. Our findings suggest that changes at the workplace have benefited other workers more than shift workers as they are still more exposed to all occupational hazards.

show abstract

Historical evolution of regulatory standards for occupational and consumer exposures to industrial talc

Cited by 14 publications

References 20 publications

Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc

Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc

Asbestos in Talc and Mesothelioma: Review of the Causality Using Epidemiology

Important Difference between Occupational Hazard Exposure among Shift Workers and Other Workers; Comparing Workplace before and after 1980

Contact Info

Product

Resources

About