Historical documentation of lead toxicity prior to the 20th century in English literature

Jonasson, M E; Afshari, Reza

doi:10.1177/0960327117737146

Cited by 26 publications

(14 citation statements)

References 93 publications

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“…Atypical sources of lead poisoning in children were reviewed some years ago [16]. In adults, it is less frequent and is mainly linked to the use of herbal remedies [5,7,8]. Food (meat, probably as in the case described due to release of metal by pots) or vegetables from soils polluted by industrial discharges (not only Pb, but other heavy metals such as cadmium and mercury) can be a source of toxicity.…”

Section: Discussionmentioning

confidence: 99%

“…In recent literature, several cases of domestic lead poisoning have been described, due to a large variety of causes such as lead pipes used for drinking water or the use of lead as a sweetener in home distillation of wine and rum [5], but also chronic use of glazed earthenware pottery [6] and retained bullets [7]. Moreover, in the last 20 years, cases of lead poisoning by traditional herbal medicine (Indian, Chinese, Ayurvedic remedies) [8] or cosmetics and by opium abuse appeared in the literature [9].…”

Section: Introductionmentioning

confidence: 99%

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Unusual Domestic Source of Lead Poisoning

Nicolli

Mina

Nuzzo

et al. 2020

IJERPH

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Non-occupational lead poisoning is not rare, mainly occurring in domestic situations in children, but also in adults. Lead poisoning was observed in a 65 years-old woman non-exposed to risk that caught our attention with a diagnostic suspicion of acute intermittent porphyria according to recurrent episodes of abdominal pain and neuropathy of upper limbs. Acute intermittent porphyria was excluded by a laboratory investigation that showed instead severe lead poisoning. After several thorough examinations of the domestic environment, the source of intoxication has been detected in some cooking pots that released high concentrations of lead. Ethylenediamine tetracetic acid disodium calcium therapy (three cycles) reduced consistently blood lead concentration and, after one year, neuropathy was almost entirely recovered.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Unusual Domestic Source of Lead Poisoning

Nicolli

Mina

Nuzzo

et al. 2020

IJERPH

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“…Pb is a persistent environmental toxin that for more than a hundred years has been known to have harmful human health effects[10]. Pb exposure in neural SCs (NSCs) was shown to slightly reduce cell proliferation[11].…”

Section: Heavy Metalsmentioning

confidence: 99%

Effects of environmental stressors on stem cells

Worley

Parker

2019

WJSC

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Environmental toxicants are ubiquitous, and many are known to cause harmful health effects. However, much of what we know or think we know concerning the targets and long-term effects of exposure to environmental stressors is sadly lacking. Toxicant exposure may have health effects that are currently mischaracterized or at least mechanistically incompletely understood. While much of the recent excitement about stem cells (SCs) focuses on their potential as therapeutic agents, they also offer a valuable resource to give us insight into the mechanisms and risks of toxicant effects. Not only as a response to the increasing ethical pressure to reduce animal testing, SC studies allow us valuable insight into the true effects of human exposure to environmental stressors under controlled conditions. We present a review of the history of publications on the effects of environmental stressors on SCs, followed by a consolidation of the literature over the past five years on a subset of key environmental stressors of importance to human health and their effects on both embryonic and tissue SCs. The review will make constructive suggestions as to areas of toxicant research where further studies are needed, as well as making indications of the potential utility for advancing knowledge and directing research on environmental toxicology.

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“…Lead is extensively used in industries and household appliances, including automobiles, soldering, welding, lead-acid batteries, plastics, paints, fuel, ceramics, food storage cans, etc 1,2 . Lead has a non-biodegradable nature and remain persistent in the environment 3 . Although the poisoning features of lead have been detected as early as 370 BC, it still remains an important growing occupational and environmental health concern 4 .…”

Section: Introductionmentioning

confidence: 99%

An Investigation of Lead Concentration in the Breathing Air and the Blood of Automobile Welders in Birjand, Iran

Motamedrezaei

Gholami

Sharifzadeh

et al. 2022

Preprint

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Introduction: Lead is known as one of the most dangerous toxic metals in the world and its entry into the body can cause acute and chronic intoxication with a wide range of systemic symptoms. Our goal in the current research is to study the level of lead in the breathing zone and blood of the automobile welders in Birjand. Methods: A cross-sectional, descriptive-analytic study was conducted on 47 automobile welders. The criteria for entering the study included, male gender, having at least 1 year of experience in automobile welding, and at least 8 hours of daily employment in welding. The general information required was collected through a questionnaire. At the beginning of the study, in each working environment air samples were taken in accordance with NIOSH 7082 standards. The analysis of the air lead concentration (ALC) was carried out by a flame atomic absorption spectrophotometer. The blood lead concentration (BLC) was measured by NIOSH 8003 method via graphite furnace atomic absorption spectrophotometer. Results: Based on the data, 12.8% of the workers were smokers and 66% used appropriate personal protective equipment. The average ALC was 0.0458 +/- 0.0296 mg/m3 and the average BLC of automobile welders was 9.89 +/- 7.32 μg/dL. Although Pearson correlation coefficient showed a positive correlation between ALCs and BLCs, this correlation was not statistically significant (p = 0.38, r = 0.18). Conclusion: The findings of this study showed that the average BLC in cigarette smokers and those who did not use PPE was higher than other people; besides, it was higher in individuals over the age of 30 than those under this age. The mean BLC in automobile welders and the mean ALC corresponded to the standards of the American Conference of Governmental Industrial Hygienists (ACGIH).

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Historical documentation of lead toxicity prior to the 20th century in English literature

Cited by 26 publications

References 93 publications

Unusual Domestic Source of Lead Poisoning

Unusual Domestic Source of Lead Poisoning

Effects of environmental stressors on stem cells

An Investigation of Lead Concentration in the Breathing Air and the Blood of Automobile Welders in Birjand, Iran

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