Historical development of cancer programs

Yarbro, Connie Henke; Yarbro, John W.

doi:10.1016/s0749-2081(05)80113-5

Cited by 7 publications

(6 citation statements)

References 2 publications

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“…15 The limited evidence suggests that almost all chemotherapeutic drugs used in ALL induction can be given during pregnancy, albeit, with risks to the fetus including still-births, intrauterine growth restrictions, spontaneous abortions, and congenital malformations, especially in the first trimester. 15 16 17 Beyond first trimester, however, almost all chemotherapeutic drugs can be used. Some modifications have also been recommended with regard to L-asparaginase and intrathecal methotrexate in view of risk of thromboembolism and fetal aminopterin syndrome.…”

Section: Discussionmentioning

confidence: 99%

Pregnancy and Acute Lymphoblastic Leukemia: A Case Series and Review of Literature

Bhattacharjee¹,

Ghosh

Ray³

et al. 2023

Indian J Med Paediatr Oncol

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Acute lymphoblastic leukemia (ALL) diagnosed during pregnancy is rare and causes ethical and therapeutic challenges. We performed a retrospective search of ALL patients (n = 202) treated at our institution from 2015 to 2020 and found five patients diagnosed during pregnancy. In this report, we discuss the individual patients in detail and the challenges faced during their treatment. The use of established lymphoblastic leukemia treatment protocols and the modifications made therein to prevent untoward chemotherapy-related toxicities to the fetus are discussed in this study. We report the second use of rasburicase during pregnancy in literature with favorable maternal and fetal outcomes. We also present an extensive literature review of 41 cases of ALL in pregnancy previously reported. It is important to note that there is a dearth of guidelines for the treatment of these complex situations, and although certain general principles can be established, an individualized approach is needed in most cases of leukemia diagnosed during pregnancy.

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Section: Discussionmentioning

confidence: 99%

Pregnancy and Acute Lymphoblastic Leukemia: A Case Series and Review of Literature

Bhattacharjee¹,

Ghosh

Ray³

et al. 2023

Indian J Med Paediatr Oncol

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“…It is the leading cause of death due to cancer for women aged 20 to 59 years of age. 1 Worldwide, breast cancer is one of the most common cancer and second leading cause of cancer death among women. 2 In India, breast cancer has ranked number one cancer among women.…”

Section: Introductionmentioning

confidence: 99%

Awareness on breast cancer among females at Bharatpur metropolitan, Chitwan, Nepal

Neupane,

Upadhyay,

Chhetri

2023

JGMC Nepal

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Introduction: Breast cancer is the most frequently diagnosed cancer in the world and second most common malignancy among Nepalese women with high prevalence. Countries with lower level of resources like Nepal, prevention of breast cancer is more important. The objective of the study was to find out the level of awareness on breast cancer among female at Bharatpur Metropolitan, Nepal. Methods: An analytical cross- sectional study was conducted among 263 female of Bharatpur Metropolitan city, Nepal. Non probability purposive sampling technique was used for data collection. Data was entered and analyzed by using SPSS-20, p-value <0.05 was considered as statistically significant. Results: The mean±SD of age was found 34.40±11.42 years. Study showed that 61.2% (with 95% CI as 55.32-67.1%) had good awareness on risk factors, 60.5% (with 95% CI as 54.54-66.36) had good awareness on warning sign and symptoms and only 44.5% (with 95% CI as 38.48-50.49) had good awareness on screening and prevention. Overall level of awareness on breast cancer was found poor (50.2%). The mean+SD of overall awareness of the respondents on breast cancer was 15.51±2.84. Statistical significant association was found between overall level of awareness and respondents’ education (p=0.039), husband education (p=0.011) and occupation (p=0.046) of the respondents. Conclusions: More than half of the respondents has poor level of awareness on breast cancer among women in Bharatpur, Chitwan, Nepal. Better health awareness among women in the community, breast cancer screening programmes and national policies to establish effective cancer literacy programs would cause a favorable and positive clinical picture in the country.

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“…[1] The cervix tumor has an invasive feature with the capacity to proliferate to surrounding organs such as the vagina, bladder, and rectum, as well as dissemination and involvement of structures distant from its place of origin. [1,2] This neoplasm is mainly caused by human papillomavirus (HPV) infection, early sexual activity with multiple partners, smoking, and prolonged use of oral contraceptives. [3] The treatment of cervical cancer has 3 aspects: surgery, chemotherapy, and radiotherapy, which can be performed alone or in combination.…”

Section: Introductionmentioning

confidence: 99%

Use of ginger to control nausea and vomiting caused by chemotherapy in patients with cervical cancer undergoing treatment

Silva¹,

Silva

Pessoa

et al. 2022

Medicine

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Introduction:Uterine cervix tumors have an invasive nature, with the capacity to proliferate to surrounding organs such as the vagina, bladder, and rectum, as well as the capacity for dissemination and involvement of structures distant from its place of origin. According to the International Federation of Gynecology and Obstetrics, patients with stages IB I, IB I microscopic (small dimension <4 cm) are indicated for radiotherapy or adjuvant chemoradiotherapy with cisplatin (40 mg/m2). However, cisplatin has side effects such as hematological implications (anemia, neutropenia, and thrombocytopenia), gastrointestinal disorders (nausea, vomiting, diarrhea, constipation), and fatigue. Zingiber officinale contains bioactive compounds that act on pregnancy and postoperative nausea, chemotherapy-induced nausea and vomiting, and also in the management of fatigue, myalgia, and insomnia. This study aimed to evaluate the effects of ginger on chemotherapy-induced nausea and vomiting in patients with cervical cancer undergoing treatment with cisplatin and radiotherapy.Methods and analyses:A randomized intervention clinical and controlled trial with a triple-blind design is described, comparing the effects of institutional antiemetic therapy alone, as well as in combination with 2 different ginger concentrations.Ethics and dissemination:Due to the nature of the study, we obtained approval from the Division Ethics Committee of Liga Contra o Câncer. All participants signed an informed consent form prior to randomization. The results of this study will be published in peer-reviewed journals. The data collected will also be available in a public repository of data.Trial registration number:This study is registered in the Brazilian Registry of Clinical Trials under number RBR-47yx6p9. This study was approved by the Division Ethics Committee of Liga Contra o Câncer under CAAE 40602320.0.0000.5293.

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Historical development of cancer programs

Cited by 7 publications

References 2 publications

Pregnancy and Acute Lymphoblastic Leukemia: A Case Series and Review of Literature

Pregnancy and Acute Lymphoblastic Leukemia: A Case Series and Review of Literature

Awareness on breast cancer among females at Bharatpur metropolitan, Chitwan, Nepal

Use of ginger to control nausea and vomiting caused by chemotherapy in patients with cervical cancer undergoing treatment

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