Abstract--End-stage temporo-mandibular joint (TMJ) disease presents a challenging biomechanical problem. The primary function of joint replacement surgery is to relieve pain and restore function, which includes transmitting physiological loads and the provision of both a physiological range of movement and an articulation with minimum friction and wear. It has been demonstrated that the use of appropriate biomaterials and design parameters can decrease material wear and increase the longevity of TMJ replacement (TMJR) devices. Therefore, as with any implanted functioning biomechanical device, surgical revisions may be necessary to remove or replace the articulating components due to material wear or failure. The purpose of this study is to evaluate the criteria for the successful use of TMJR devices and thereby establish a rationale for the use of these devices in the longterm management of end-stage TMJ disorders.Keywords--Cobalt-chromium alloys for surgical implants, ultra-high molecular weight polyethylene for surgical implants, titanium alloys for surgical implants, total joint replacement, temporomandibular joint.