Historic concepts of dementia and Alzheimer's disease: From ancient times to the present

Vatanabe, Izabela Pereira; Manzine, Patrícia Regina; Cominetti, Márcia Regina

doi:10.1016/j.neurol.2019.03.004

Cited by 18 publications

(6 citation statements)

References 28 publications

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“…Dementia is a syndrome caused by brain lesions, mainly characterized by cognitive impairment, and may be accompanied by hallucinations, delusions, personality changes, and behavioral disorders (Vatanabe, Manzine, & Cominetti, 2019). With the increasing population of aging, patients with dementia have brought tremendous burdens to the world's health and economy (Alzheimer's Disease International, 2018).…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Non‐Pharmacological Interventions on Apathy in Patients With Dementia: A Systematic Review of Systematic Reviews

Cai

et al. 2020

Worldviews Ev Based Nurs

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Background Apathy is one of the behavioral and psychological symptoms of dementia (BPSD), which is the most frequent and can accelerate the progress of dementia. Aims To systematically review the evidence of effectiveness of non‐pharmacological interventions on apathy in patients with dementia. Methods Databases including the Cochrane Library, Joanna Briggs Institute (JBI) Library, PubMed, EMBASE, CINAHL, PsycINFO, Psychology and Behavioral Sciences Collection, CNKI, and Wan Fang Data were searched for systematic reviews of the effectiveness of non‐pharmacological interventions on apathy in patients with dementia. AMSTAR 2 was applied to assess the methodological quality of reviews. Results Nine systematic reviews were included. The average level of overall confidence for included systematic reviews was low. Among all the non‐pharmacological interventions involved in this review, the effectiveness of multisensory stimulation, music therapy, cognitive stimulation, and pet therapy was relatively robust. The effects of reminiscence therapy, therapeutic conversation, progressive muscle relaxation, art therapy, exercise therapy, occupational therapy, dementia special care units, nursing staff education, and comprehensive interventions need to be validated further. Meanwhile, the current evidence failed to support the effects of psychomotor therapy and validation therapy on apathy. Linking Evidence to Action Non‐pharmacological interventions for apathy in patients with dementia are acceptable. In spite of requirements for adequate and high‐quality original studies and quantitative systematic reviews to validate the efficacy of non‐pharmacological interventions, multisensory stimulation, music therapy, cognitive stimulation, and pet therapy are deemed the most helpful according to evidences available.

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Section: Introductionmentioning

confidence: 99%

The Effectiveness of Non‐Pharmacological Interventions on Apathy in Patients With Dementia: A Systematic Review of Systematic Reviews

Cai

et al. 2020

Worldviews Ev Based Nurs

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“…A study states that, “Dementia is a complete forgetting of preceding state, biased judgement, reciprocated act of exaggeration, simultaneous alteration of ideas” . It seemed, however, that chronic dementia causation was still misleading and was linked with stress, alcohol, masturbation, and exorbitant study . The modern concept of dementia constitutes the tripod changes, viz., behavioral changes, cognitive changes, and deterioration of daily activities .…”

Section: Unraveling the Historical Journey Of Alzheimer’s Diseasementioning

confidence: 99%

Investigating the Potential Impact of Air Pollution on Alzheimer’s Disease and the Utility of Multidimensional Imaging for Early Detection

Singh S,

Ansari,

M. Elossaily

et al. 2024

ACS Omega

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Pollution is ubiquitous, and much of it is anthropogenic in nature, which is a severe risk factor not only for respiratory infections or asthma sufferers but also for Alzheimer's disease, which has received a lot of attention recently. This Review aims to investigate the primary environmental risk factors and their profound impact on Alzheimer's disease. It underscores the pivotal role of multidimensional imaging in early disease identification and prevention. Conducting a comprehensive review, we delved into a plethora of literature sources available through esteemed databases, including Science Direct, Google Scholar, Scopus, Cochrane, and PubMed. Our search strategy incorporated keywords such as "Alzheimer Disease", "Alzheimer's", "Dementia", "Oxidative Stress", and "Phytotherapy" in conjunction with "Criteria Pollutants", "Imaging", "Pathology", and "Particulate Matter". Alzheimer's disease is not only a result of complex biological factors but is exacerbated by the infiltration of airborne particles and gases that surreptitiously breach the nasal defenses to traverse the brain, akin to a Trojan horse. Various imaging modalities and noninvasive techniques have been harnessed to identify disease progression in its incipient stages. However, each imaging approach possesses inherent limitations, prompting exploration of a unified technique under a single umbrella. Multidimensional imaging stands as the linchpin for detecting and forestalling the relentless march of Alzheimer's disease. Given the intricate etiology of the condition, identifying a prospective candidate for Alzheimer's disease may take decades, rendering the development of a multimodal imaging technique an imperative. This research underscores the pressing need to recognize the chronic ramifications of invisible particulate matter and to advance our understanding of the insidious environmental factors that contribute to Alzheimer's disease.

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“…In 1910, in the eighth edition of Clinical Psychiatry: A Text-book for Students and Physicians, Kraepelin discussed a special group of cases with very severe cell transformations that involve too many plaques, the death of about one-third of the cerebral cortex, replacing them with specific bursts of coloured neurofibrils, and represent the most severe form of malnutrition. Kraepelin, who offered a description at a time when the clinical definition of AD was unclear [9], was the first to coin the condition as ''Alzheimer's disease''. The diagnosis of the Auguste Deter disease (the first case was introduced in 1906 by the German psychiatrist Alois Alzheimer) was somewhat ambiguous; after more than 100 years, credible descriptions for the clinical definition of AD started to surface.…”

Section: A Alzheimer's Diseasementioning

confidence: 99%

Alzheimer’s Diseases Detection by Using Deep Learning Algorithms: A Mini-Review

2020

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The accurate diagnosis of Alzheimer's disease (AD) plays an important role in patient treatment, especially at the disease's early stages, because risk awareness allows the patients to undergo preventive measures even before the occurrence of irreversible brain damage. Although many recent studies have used computers to diagnose AD, most machine detection methods are limited by congenital observations. AD can be diagnosed-but not predicted-at its early stages, as prediction is only applicable before the disease manifests itself. Deep Learning (DL) has become a common technique for the early diagnosis of AD. Here, we briefly review some of the important literature on AD and explore how DL can help researchers diagnose the disease at its early stages. INDEX TERMS Alzheimer's disease, deep learning, early stage detection and diagnosis.

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Historic concepts of dementia and Alzheimer's disease: From ancient times to the present

Cited by 18 publications

References 28 publications

The Effectiveness of Non‐Pharmacological Interventions on Apathy in Patients With Dementia: A Systematic Review of Systematic Reviews

The Effectiveness of Non‐Pharmacological Interventions on Apathy in Patients With Dementia: A Systematic Review of Systematic Reviews

Investigating the Potential Impact of Air Pollution on Alzheimer’s Disease and the Utility of Multidimensional Imaging for Early Detection

Alzheimer’s Diseases Detection by Using Deep Learning Algorithms: A Mini-Review

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