Histoplasmosis presenting as hypoadrenalism

Abstract

Histoplasmosis is considered to be rare in India. Adrenal involvement is common in disseminated disease but may be the only site of demonstrable disease sometimes. We describe the case of a 36-year-old lady with type 2 diabetes mellitus who presented with adrenal insufficiency in whom computed tomography and fine needle aspiration cytology helped in establishing the diagnosis. A high index of clinical suspicion and appropriate use of invasive diagnostic methods will be helpful in early diagnosis and institution of appropriate treatment.