Histoplasma panniculitis

Abildgaard, W. H.

doi:10.1001/archderm.121.7.914

Cited by 7 publications

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“…However, H. capsulatum var. capsulatum has been identified in erythema nodosum‐like nodules and in “histoplasma panniculitis” 5,25 . In their report on “histoplasma panniculitis”, Abildgaard et al.…”

Section: Discussionmentioning

confidence: 99%

Disseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus

et al. 2002

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Section: Discussionmentioning

confidence: 99%

Disseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus

et al. 2002

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“…Cutaneous involvement is reported in 4–15% of patients with disseminated histoplasmosis, but it was observed in none of 45 cases from 3 recent case series . Histoplasma ‐associated infective panniculitis is a very rare complication with only 15 compatible cases reported in the literature, including 5 in SOTR . This case report illustrates the diagnostic challenges of this rare clinical entity, which was misdiagnosed as EN.…”

Section: Discussionmentioning

confidence: 82%

“…Granuloma formation has been described as a remarkable, yet inconsistent feature of fungal panniculitis . In the 15 previously reported cases of Histoplasma panniculitis , inflammation was predominantly lobular, septal, and mixed in 2, 3, and 3, respectively; it was not specified in 7 cases. Granulomas were described in 3 cases and necrosis was seen in 3 (all in cases with septal predominance), 2 of which were associated with vasculitis.…”

Section: Discussionmentioning

confidence: 95%

“…Histoplasma capsulatum , a dimorphic fungus that is endemic along the Mississippi, Ohio, and St. Lawrence Rivers , has been incriminated in both EN and infective (fungal) panniculitis . Although the former has been described in acute self‐limited forms, the latter is seen in progressive disseminated histoplasmosis (PDH) , a form arising in immunocompromised patients, such as solid organ transplant recipients (SOTR), who fail to mount an appropriate cellular immune response. EN‐like lesions are a rare occurrence in SOTR; however, establishing an etiologic diagnosis is critical – albeit very challenging at times – in order to assure appropriate therapy.…”

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confidence: 99%

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Histoplasmosis and subcutaneous nodules in a kidney transplant recipient: erythema nodosum versus fungal panniculitis

Dufresne

LeBlanc

Zhang

et al. 2013

Transplant Infectious Dis

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Erythema nodosum (EN)-like lesions are a rare occurrence after solid organ transplantation. Differential diagnosis includes infective panniculitis, which can be a feature of progressive disseminated histoplasmosis (PDH), an uncommon but severe form affecting primarily immunocompromised hosts. We report on a fatal case of PDH, which presented as fungal panniculitis masquerading as EN in a renal allograft recipient 25 years after transplantation. We discuss the clinical, histopathological, and microbiological characteristics of this rare complication, with focus on its distinction from EN. This case emphasizes the central role of biopsy in transplant recipients presenting with cutaneous lesions, and the importance of clinicopathologic correlation and complementary microbiological investigations.

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“…Presenting skin lesions are nonspecific, consisting of multiple, diffuse, tender, erythematous to violaceous, nonfluctuant nodules, which can become persistent or confluent if long lived. Mucocutaneous plaques or nodules that often ulcerate are commonly seen in disseminated histoplasmosis infections that have subcutaneous involvement, whereas localized, nontender ulcer(s) and lymphangitis are more typical of primary inoculation infections (39–41). Ulcerations and vegetations associated with disseminated infection may also be seen.…”

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confidence: 99%

Infection and panniculitis

Morrison¹,

Rapini²,

Willison

et al. 2010

Dermatologic Therapy

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Infection-induced panniculitis may result from a number of microbes including bacteria, fungi, and parasites. Viruses have also been implicated as a cause. This type of panniculitis can occur as a primary infection by direct inoculation of infectious microorganisms into the subcutaneous tissue, or secondarily via microbial hematogenous dissemination with subsequent infection of the subcutaneous tissue. Panniculitis is rarely viewed solely in terms of infectious causes. Also, subcutaneous infections are infrequently viewed in terms of infection-induced panniculitis but rather as cutaneous infections with subcutaneous involvement. Little information exists specifically on the subject of infection-induced panniculitis outside of the realm of case reports and case series. In this review, the present authors address panniculitis from the vantage point of infectious causes, focusing on those microorganisms with infection-induced panniculitis reports in the literature. Diagnosis and treatment are also discussed.

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Histoplasma panniculitis

Cited by 7 publications

References 0 publications

Disseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus

Disseminated cutaneous histoplasmosis in patients infected with human immunodeficiency virus

Histoplasmosis and subcutaneous nodules in a kidney transplant recipient: erythema nodosum versus fungal panniculitis

Infection and panniculitis

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