1999
DOI: 10.1016/s0194-5998(99)80334-9
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Histopathology of submandibular glands removed for sialolithiasis

Abstract: We reviewed the clinical history of 48 consecutive patients who underwent submandibular gland removal for radiologically proven sialolithiasis. The specimens were examined by a pathologist blinded to the clinical data. A histopathologic classification into 1 of 3 grades was established by evaluating the degrees of atrophy, fibrosis, and inflammation. A correlation between the clinical and pathological variables was sought in order to define clinical variables that would predict abnormal submandibular glands th… Show more

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Cited by 31 publications
(47 citation statements)
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“…This effect is likely due to the parotid gland consisting mostly of serous cells, which are more prone to injury from RAI treatment (19). Traditional methods of treating nonneoplastic disorders of the salivary glands are conservative treatment or salivary gland excision (20). Conservative therapy, consisting of salivary massage, sialagogues, and hydration, has been found to control symptoms in 71% of patients in one study (15).…”
Section: Discussionmentioning
confidence: 99%
“…This effect is likely due to the parotid gland consisting mostly of serous cells, which are more prone to injury from RAI treatment (19). Traditional methods of treating nonneoplastic disorders of the salivary glands are conservative treatment or salivary gland excision (20). Conservative therapy, consisting of salivary massage, sialagogues, and hydration, has been found to control symptoms in 71% of patients in one study (15).…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, sialolithiasis is the most frequent reason for submandibular gland resection. 6,7 Sialendoscopy 4,8,9 is a new procedure for visualizing the lumen of the salivary ducts, as well as diagnosing and treating ductal diseases. Because of the required equipment and the complexity, the duration, and the potential complications of the procedure, it appears important to distinguish two different procedures: diagnostic sialendoscopy and interventional sialendoscopy.…”
Section: Introductionmentioning
confidence: 99%
“…Removal of obstruction from the ductal system usually cures the ailment, even if long standing calculi are present [14]. According to literature, patients with submandibular gland disorders have an excellent prognosis [15]. Submandibular gland removal may be indicated following failure of lithotripsy or if the size of an intraglandular stone reaches 12 mm or more as the success of lithotripsy may be less than 20 % in such cases [9].…”
Section: Discussionmentioning
confidence: 99%