Histopathological Study of Tumours of Epidermis and Epidermal Appendages

Uplaonkar, Shilpa V.; Tengli, Mandakini B.; Farheen, Syeda Saba; Pratima, S

doi:10.21088/ijprp.2278.148x.62(pt-ii)17.22

Cited by 3 publications

(5 citation statements)

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“…[12][13][14] In the current study, majority of the cases were keratinocytic tumor 81 (66.9%) followed by skin appendageal 23 (19.0%) and melanocytic tumors 17 (14.0%) similar to the study done by Uplaonkar VS, et al in which out of 36 cases studied, keratinocytic, appendageal and melanocytic tumor were 41.7%, 38.9% and 19.4% respectively. 15 In the study done by Pappala P, et al among the 43 cases, keratinocytic, melanocytic and appendageal tumor were 60.52%, 23.3% and 16.3% respectively. 10 Similar to our study Bari V, et al also found keratinocytic tumor as the commonest tumor.…”

Section: Discussionmentioning

confidence: 93%

Benign Skin Neoplasms among the Histopathological Specimens of Skin Neoplasm in a Teaching Hospital: A Descriptive Cross-sectional Study

et al. 2021

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Introduction: Skin tumors are relatively uncommon malignancies worldwide, but its incidence has been progressively increased over the last few decades. Skin tumor belongs to a diverse group of neoplasms arising from the epidermis, adnexal structures and dermis rendering the classification difficult. The study aims to find out the prevalence of benign skin neoplasm among the histopathological specimens of skin neoplasm of a teaching hospital. Methods: A descriptive cross-sectional study among the hospital records of histopathological samples of skin neoplasm in the Department of Pathology of a tertiary care center from January 2017 to December 2020. Ethical approval was taken from the Institutional Review Committee (Ref: MEMG/IRC/427/GA). Convenient sampling was done. Data were entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 21 software. Point estimate at 95% Confidence Interval was calculated with frequency and descriptive statistics. Results: Out of total skin neoplasm samples, 121 (57.34%) (50.67-64.01 at 95% Confidence Interval) benign skin neoplasms were present. Among them, the majority were keratinocytic tumor 81 (66.9%) followed by skin appendageal 23 (19.0%) and melanocytic tumors 17 (14.0%). Acrochordan 18 (14.9%) and pilomatricoma 12 (9.9%) were the predominant keratinocytic and appendageal neoplasms respectively. Most of the cases occurred in head and neck region 64 (52.9%). Conclusions: The study concluded that the prevalence of benign skin neoplasm was slightly lower compared to the other studies. Most of the benign skin neoplasms were keratinocytic tumors followed by appendageal and melanocytic tumors. Acrochordan was the commonest benign keratinocytic tumor.

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Section: Discussionmentioning

confidence: 93%

Benign Skin Neoplasms among the Histopathological Specimens of Skin Neoplasm in a Teaching Hospital: A Descriptive Cross-sectional Study

et al. 2021

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“…[14][15][16][17] Similarly, thrombocytopenia with or without leucopenia is also observed in malaria and enteric fever. [18][19][20][21][22][23] Thrombocytopenia with leucocytosis is commonly observed in Scrub typhus and leptospirosis. [24][25][26][27][28][29] Increased hepatic enzymes with or with hyperbilirubinemia may occur in dengue, Scrub typhus, leptospirosis and enteric fever.…”

Section: Discussionmentioning

confidence: 99%

Scrub typhus: emerging as a co-infection of acute undifferentiated febrile illness in children in a district hospital of Eastern India

Bandyopadhyay

Amin

2023

Int J Contemp Pediatr

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Scrub typhus, a zoonosis, caused by Orientia tsuttsutgamushi is transmitted to man through bite of infected tromboculid mite. It is endemic in India as other other South-east Asia countries of Tsuttsutgamuhi triangle and affects children as well. It generally presents as an acute febrile illness with non-specific features like headache rash, lymphadenopathy resembling many other commonly prevalent febrile infections. An eschar, though pathognomonic of Scrub typhus, is often missed clinically. Therefore, a high index of clinical suspicion is essential to establish a diagnosis of Scrub typhus and hence it remains usually under-diagnosed in any undifferentiated febrile illness. In this case series including three cases, we decided to rule out Scrub typhus as a co-infection when there was persistence of fever associated with thrombocytopenia even after ongoing treatment of the primarily diagnosed infection. An eschar was incidentally detected in one case only.

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“…Haematological changes are common in typhoid fever and may include anaemia, leukopenia or leukocytosis, and sometimes thrombocytopenia. 6 Haemoglobin (Hb) counts are typically unaffected, but certain complications, such as GI bleeding, haemophagocytosis, bone marrow suppression, and prolonged toxaemia may result in anaemia. 7 As a rule, patient's Hb level is always normal at the initial stage of infection and may decline slowly, depending on the progression of the disease.…”

Section: Enteric Fevermentioning

confidence: 99%

“…7 As a rule, patient's Hb level is always normal at the initial stage of infection and may decline slowly, depending on the progression of the disease. 6 Significant anaemia at the onset of a fever may point to an alternative diagnosis, like malaria.…”

Section: Enteric Fevermentioning

confidence: 99%

“…21 A low PLT count can also be observed in dengue fever (DF), but PLT counts tend to fall later in dengue and are often normal at the onset of infection; a finding that can help differentiate DF from malaria. Kumar et al analysed haematological parameters between the two diseases and suggested a combination of four variables, which, when taken together, have a post-test probability of 69% and a positive likelihood ratio of 7.2 for malaria if all 4 are present; Hb <10.0g/dL, TLC <5.0×10 6 , PLT <100,000/μl, and red cell distribution width (RDW) >15. 17…”

Section: Malariamentioning

confidence: 99%

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Utilization of the complete blood count in diagnosing endemic diseases in Pakistan

Khalid,

Umer

2023

J Pak Med Assoc

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Numerous infectious diseases, including enteric fever, malaria, dengue fever, and, most recently, coronavirus disease-2019, are prevalent in Pakistan. All these diseases have overlapping clinical symptoms and can present a diagnostic challenge for the general practitioner. Since definitive testing for these disorders is time-consuming and expensive, basic clinical testing, such as a complete blood count, should be utilised to supplement clinical diagnosis, when possible. The current narrative review was planned to present specific alterations in haematological parameters for each of these disorders. The review was intended as a guide for practising physicians in their decision-making. Key Words: Complete blood count, Typhoid fever, Malaria, Dengue, COVID-19.

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Histopathological Study of Tumours of Epidermis and Epidermal Appendages

Cited by 3 publications

References 0 publications

Benign Skin Neoplasms among the Histopathological Specimens of Skin Neoplasm in a Teaching Hospital: A Descriptive Cross-sectional Study

Benign Skin Neoplasms among the Histopathological Specimens of Skin Neoplasm in a Teaching Hospital: A Descriptive Cross-sectional Study

Scrub typhus: emerging as a co-infection of acute undifferentiated febrile illness in children in a district hospital of Eastern India

Utilization of the complete blood count in diagnosing endemic diseases in Pakistan

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