Histopathological study of neoplastic lesions of large intestine in Kashmir Valley, India

Rasool, Mohsinul; Mubeen, Basharat; Andrabi, Riyaz-u-Saif; Hamid, Sajad; Rasool, Zubaida; Shah, Parveen; Shah, Omer Javid

doi:10.5455/2320-6012.ijrms20140890

Cited by 6 publications

(1 citation statement)

References 15 publications

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“…14 The commonest site of CRC was sigmoid colon in 32 (44.44%) cases, followed by rectum in 15 (20.83). Similar results were obtained by Rasool M et al 15 and Sharma P et al 9 In the present study, most (88.9%) of the CRC were moderately differentiated adenocarcinomas, followed by well differentiated (9.7%) and poorly differentiated adenocarcinomas (1.4%).…”

Section: Discussionsupporting

confidence: 92%

Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra

Lakhe

Patil

Doshi

et al. 2023

JDPO

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Colorectal cancer is the third most common cancer in both men and women. Environmental and genetic factors play a role in the development of colorectal carcinomaThe majority of colorectal cancers are sporadic, with hereditary cancer syndrome accounting for 10% of cases. Precursor lesions like adenoma that transform into adenocarcinoma cause the majority of colorectal cancers. : A total of 72 of colorectal malignancies were studied for histopathological features. The histologic features were studied for site, grade, tumor -infiltrating lymphocytes, Crohn -like lymphocytic reaction, mucinous histology, signet ring cell histology, and medullary growth pattern.: The mean age of the patients was 59.52 ± 11.80 years with M:F 1.76:1. Light microscopy showed TILs in 16 (22.2%) patients, followed by mucinous areas in 5 (6.9%), crohn like lymphocytic reaction in 4 (5.6%) and signet ring morphology in 2 (2.8%) patients.This study concludes that colorectal carcinomas are more common in 5th and 6th decade of life with slight male preponderance. The most common malignant lesion being moderately differentiated adenocarcinomas. This study highlights age and gender prevalence, as well as histopathological characteristics of colorectal carcinomas in this demographic region .

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Section: Discussionsupporting

confidence: 92%

Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra

Lakhe

Patil

Doshi

et al. 2023

JDPO

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Histopathological spectrum of colorectal carcinomas

Nandish¹,

Sowmya²

2019

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Utility of Colonoscopic Biopsies in Histomorphological Spectrum of Colorectal Lesions - A Study in a Tertiary Care Centre in Aurangabad Region of Maharashtra

Pingle¹

2021

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BACKGROUND Colonoscopy is considered as a diagnostic procedure of choice for patients presenting with chronic diarrhoea / bloody diarrhoea. Colonoscopic mucosal biopsies have shown to be accurate indicators of extent of the involvement of colon in inflammatory bowel disease. Also, colonoscopy is still considered as the gold standard in cancer surveillance. The present study was undertaken to find out the utility of colonoscopic biopsies in histomorphological spectrum of colorectal lesions. METHODS This was a three-year retrospective study carried out in the Department of Pathology, at MGM Medical College, Aurangabad. Patient’s clinical details, colonoscopic findings and apparent pathology were noted in 206 cases along with final histopathological diagnosis. Biopsies which showed significant findings were included in the study. RESULTS In the study, the male to female ratio was 2.4 : 1. Out of 206 colorectal biopsies, 146 (70.8 %) were non-neoplastic and 60 (29.2 %) were neoplastic lesions. Amongst non-neoplastic lesions, maximum cases were of chronic colitis with 4 cases of granulomatous colitis and 30 cases of inflammatory bowel disease. Adenocarcinoma was the most common histologic type in neoplastic lesions (66.6 %), with rectum being the most common site followed by colonic polyps (25 %). As far as age group was concerned, the 2nd decade was dominated by chronic colitis, 3rd decade by adenomatous polyps and 5th decade by adenocarcinoma. CONCLUSIONS Histomorphological profile of colorectal biopsies has a wide spectrum ranging from infectious diseases, inflammatory bowel disorders to colorectal malignancies. Histopathology with correlation of clinical and endoscopic findings plays a major role in accurate diagnosis of colorectal lesions. KEYWORDS Colonoscopy, Biopsies, Neoplastic, Non-Neoplastic, Colitis, Adenocarcinoma

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Histopathological study of neoplastic lesions of large intestine in Kashmir Valley, India

Cited by 6 publications

References 15 publications

Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra

Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra

Histopathological spectrum of colorectal carcinomas

Utility of Colonoscopic Biopsies in Histomorphological Spectrum of Colorectal Lesions - A Study in a Tertiary Care Centre in Aurangabad Region of Maharashtra

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