Histopathological kidney changes and myoglobinuria in neotropical non‐human primates attacked by dogs, Brazil

Abstract

Background Non‐human primates (NHPs) are susceptible to dogs’ attacks, events that may cause muscle damage along with stress, and could be in some extent compatible with capture myopathy, a syndrome that results in myoglobinuria and renal damage. Methods We aimed to evaluate by histopathology pre‐existing lesions and subsequent sequelae related to dogs’ attacks, acute tubular necrosis (ATN) and myoglobinuria, as well as the usefulness of Pearls Stain and IHC to diagnose it. Histopathology was performed in available organs, and sections of kidney submitted to Prussian blue stain and myoglobin immunohistochemistry. Results During January 2014—June 2016, 16/145 (11%) of NHPs received by Adolfo Lutz Institute, Brazil were reported as attacked by dogs. A high frequency of young and debilitated animals was found. Myoglobinuria was observed in more than half animals (9/16; 56.2%), from which (5/9; 55.5%) presented ATN. Conclusions Kidney lesions are plausible findings in NHPs attacked by dogs.

Non-thrombotic pulmonary embolism of brain, liver, or bone marrow tissues associated with traumatic injuries in free-ranging neotropical primates

“…10 However, this also makes them more exposed to anthropogenic trauma, such as electrocution, roadkill, dog attack, and direct human aggression. 6,15,22,27 Importantly, in our study, Callithrix spp. (marmosets) were the main genus affected by traumatic events, and although it was not possible to precisely identify the cause of the trauma, blunt and sharp trauma represented more than 90% of the cases, and the head was the most commonly affected site in marmosets.…”

“…8,23,25,30 In free-ranging New World (neotropical) primates (NWP), traumatic injuries are important and prevalent, usually associated with periurban NWP populations and anthropogenic factors, and often have a negative impact on NWP conservation strategies. 6,15,22,27…”

“…8,23,25,30 In free-ranging New World (neotropical) primates (NWP), traumatic injuries are important and prevalent, usually associated with periurban NWP populations and anthropogenic factors, and often have a negative impact on NWP conservation strategies. 6,15,22,27 Non-thrombotic pulmonary embolism (NTPE) may be a consequence of trauma, but it is less common than pulmonary thromboembolism. NTPE is defined as the occlusion of pulmonary arteries and capillaries by non-thrombotic material, including adipose tissue, bone marrow, foreign material, gas, neoplastic cells, or infectious agents.…”