Histopathological Investigations on the Localization, Number, Activity and Extent of Otosclerotic Foci

Nylén, B

doi:10.1017/s0022215100046533

Cited by 74 publications

(10 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other reports have also shown this area to be the most common site of otosclerosis involvement [2,12], In this study, because the CT density around the cochlea had no significant differ ence between the otosclerosis and the control groups, many of our subjects were thought to have stapedial oto sclerosis with no cochlear involvement. As surgical treat ment can only improve the conductive portion of the hearing loss caused by the fixation of the stapes, the densi ty measurement in the area anterior to the oval window was considered quite important for the clinical diagnosis of stapedial otosclerosis.…”

Section: Discussionmentioning

confidence: 62%

Computed Tomographic Image Analysis of Ears with Otosclerosis

Miura

Naito²,

Takahashi³

et al. 1996

ORL

View full text Add to dashboard Cite

To evaluate the usefulness of quantitative analysis of computed tomographic images in diagnosing stapedial otosclerosis, high-resolution temporal bone computed tomography (CT) of 32 ears with otosclerosis and 19 control ears was used. The images on the section containing the oval window were digitized using a scanner, and the ratio of the mean gray scale value of 5 areas in the otic capsule including the area anterior to the oval window to that of the cortical bone was calculated. The mean value of the ratio of the area anterior to the oval window was significantly lower in the otosclerosis group (0.85 ± 0.10) than in the control group (1.03 ± 0.03; Student t test: t = 7.94, p < 0.0001). In 30 of 32 (93.7 %) otosclerotic ears, the values were lower than the normal range calculated in the control group. This method of quantitative CT image analysis comparing the area anterior to the oval window was considered useful in diagnosing stapedial otosclerosis.

show abstract

Section: Discussionmentioning

confidence: 62%

Computed Tomographic Image Analysis of Ears with Otosclerosis

Miura

Naito²,

Takahashi³

et al. 1996

ORL

View full text Add to dashboard Cite

show abstract

“…Other common sites for developing otosclerotic foci are the round window and bulge of the promontory, occurring in 35 to 40% of cases (6,24). CO has been reported to result in hearing loss, which defines clinical otosclerosis, in only approximately 0.5 to 1% of cases (1,32). Of course, the hearing loss is more commonly the conductive type, resulting from stapes footplate fixation, but it has been estimated that 3% of clinical cases involve lesions that have spread to the cochlea, resulting in a progressive sensory hearing loss.…”

Section: Discussionmentioning

confidence: 99%

Spiral Ligament and Stria Vascularis Changes in Cochlear Otosclerosis: Effect on Hearing Level

Doherty¹,

Linthicum²

2004

Otology & Neurotology

View full text Add to dashboard Cite

show abstract

“…Nylen (1949) found that 70 to 80% of cases were involved bilaterally and were symmetrical in the areas of involvement. Nagen (1947) found histologically unilateral otosclerosis in 10% of temporal bones.…”

Section: Sites Of Involvementmentioning

confidence: 98%

“…Very rarely will the round window be occluded by otosclerosis, with complete obliteration of the round window accounting for 6% of temporal bones examined (Hueb et al 1991). Reports of round window involvement range from 30 to 50% (Guild 1944;Nylen 1949). It was also noted, however, that despite being very close to the round window, otosclerotic focus merged in approximately 12% of cases (Nager 1969).…”

Section: Sites Of Involvementmentioning

confidence: 99%