Histopathological comparison between endofibrosis of the high-performance cyclist and atherosclerosis in the external iliac artery

Vink, Annemieke; Bender, Mart; Schep, Goof; Wichen, D.F. van; Weger, Roel A. de; Pasterkamp, Gérard; Moll, Frans L.

doi:10.1016/j.jvs.2008.07.057

Cited by 41 publications

(25 citation statements)

References 13 publications

(25 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On CTA or MRA wall thickening and luminal narrowing, without aneurysm formation can be seen. Cases of luminal thombosis have been also reported [57,58].…”

Section: Iliac Endofibrosismentioning

confidence: 97%

Management of peripheral arterial disease: Role of computed tomography angiography and magnetic resonance angiography

et al. 2011

View full text Add to dashboard Cite

“…On CTA or MRA wall thickening and luminal narrowing, without aneurysm formation can be seen. Cases of luminal thombosis have been also reported [57,58].…”

Section: Iliac Endofibrosismentioning

confidence: 97%

Management of peripheral arterial disease: Role of computed tomography angiography and magnetic resonance angiography

et al. 2011

View full text Add to dashboard Cite

“…1,2,7,12,18,19 The histology of these lesions is distinct from atherosclerosis and fibromuscular dysplasia. Common findings include intimal thickening or hyperplasia, with myofibroblast proliferation identified by actin staining, 1,2,7-10,20 spindle-shaped or stellate cells, 9,21 collagen deposition, 20,21 and formation of a neointimal elastic membrane. 2,9,10,21 In addition, medial hypertrophy or foci of medial fibrosis and adventitial thickening have been reported.…”

Section: Discussionmentioning

confidence: 99%

Results of external iliac artery reconstruction in avid cyclists

Politano

Tracci

Gupta

et al. 2012

Journal of Vascular Surgery

View full text Add to dashboard Cite

External iliac arteriopathy is a disease of prolonged, sustained, and repetitive trauma. Patch angioplasty yields a low rate of reoperation, more satisfied patients, return to competitive activity, and improvement in postexercise ankle-brachial indices. Interposition grafting is associated with slightly older patients, more extensive disease, and less satisfying results. Intimal hyperplasia is the most frequent complication necessitating reoperation. Both the decision to pursue arterial reconstruction and patient expectations must be tempered by the pattern of disease and the potential for unsatisfactory results.

show abstract

“…However, in contrast to FMD, endofi brosis often is bilateral, is more diffuse in nature, and almost exclusively involves the external iliac arteries [17]. • A recent report of 19 histopathologic specimens of endofi brosis demonstrated loose connective tissue with moderate to high cellularity, loose collagen fi bers, and a dearth of infl ammatory cells compared with atherosclerotic specimens [22]. Endofi brosis is thought to be a result of repeated trauma to the vessel caused by stretching and compression of the external iliac artery at the level of the hip, compression by the psoas muscle, tethering from psoas muscle arteries, and shear forces due to enhanced blood fl ow to the lower extremities [23].…”

Section: Endofi Brosis Of the Iliac Arterymentioning

confidence: 99%

Unusual causes of intermittent claudication: Popliteal artery entrapment syndrome, cystic adventitial disease, fibromuscular dysplasia, and endofibrosis

Korngold¹,

Jaff

2009

Curr Treat Options Cardio Med

View full text Add to dashboard Cite

In the general population, vascular causes of exercise-induced limb discomfort are most often the result of peripheral artery disease (PAD) due to atherosclerosis. However, several other clinical entities can often mimic the symptoms of atherosclerotic PAD of the lower extremities, particularly among younger patients with fewer risk factors for atherosclerosis, who often are more athletically fit than patients with PAD. Treatment for these entities often requires percutaneous or surgical intervention. This article reviews four uncommon vascular causes of exercise-induced limb discomfort: popliteal artery entrapment syndrome, cystic adventitial disease of the popliteal artery, fibromuscular dysplasia of the lower-extremity arteries, and endofibrosis of the iliac artery.

show abstract

Histopathological comparison between endofibrosis of the high-performance cyclist and atherosclerosis in the external iliac artery

Abstract: In the external iliac artery, atherosclerotic lesions and endofibrotic lesions of high performance cyclists have distinct morphologic characteristics. Endofibrosis in the external iliac artery may serve as soil for luminal thrombosis.

Cited by 41 publications

References 13 publications

Management of peripheral arterial disease: Role of computed tomography angiography and magnetic resonance angiography

Management of peripheral arterial disease: Role of computed tomography angiography and magnetic resonance angiography

Results of external iliac artery reconstruction in avid cyclists

Unusual causes of intermittent claudication: Popliteal artery entrapment syndrome, cystic adventitial disease, fibromuscular dysplasia, and endofibrosis

Contact Info

Product

Resources

About