Histopathological and radiographic evaluation of rat molar teeth after traumatic injury-a pilot study

Abstract

Objective:Radiographic and histopathological evaluation of mechanical trauma on the development of maxillary molars in rat.Materials and Methods:Experimental study with 7-day-old five new born Wistar rats. Trauma induced on 7th postnatal day with #55 K file. Right first molar region of the maxilla was the experimental side, and the left side as control. Each animal was sacrificed for histopathological observation on 8th day (immediately next day of injury), 10th day (after 3 days of injury), 13th day (Enamel completion), 19th day (Emergence into oral cavity) and 42nd day when all the teeth came into functional occlusion.Results:On the 42nd day experimental side of the study, the 1st molar tooth had not erupted and the radiographs taken revealed conglomerate mass suggestive of complex odontome. Reduced tooth size, altered enamel and dentin formation, abscess formation and complex odontome like structure were observed histopathologically.Conclusion:The diversity of morphlogical and histopathological changes to intrusive force implies intricate mechanism involved in tooth development.

Toxic Effect of Cadmium Chloride Exposure on Teeth Development in Sprague Dawley Rats During Pregnancy

“…Results of the control group showed early bell stage with early differentiation of odontoblasts at the cusp region at the GD17, fully differentiated odontoblasts along the pulpal wall with deposited dentin at PND10 sections and at PND20 fully formed crown with central cup penetrating the oral mucosa. These findings are in agreement with control group of previous researches (Lukinmaa et al, 2001;Silva et al, 2010;Prasanth and Saraswathi, 2012). Meanwhile, CdCl2 group data showed delayed stages in comparison with the control group in all time periods.…”

An enigmatic ectopic eruption of odontoma

“…5 The present case features an uncommon extraoral odontoma with a complicated morphology. Early trauma to dental machinery, illness, hereditary conditions (such as Gardner's syndrome), and gene variations can trigger the growth of an odontoma instead of a tooth, 6,7 according to reports.…”

The Effect of Chicken Bone Powder Supplementation during Pregnancy and Lactation on the Calcium Level of Rat Pups’ Teeth

“…In this study, rat pups' teeth were taken at 15 d after birth. The calcification process of incisors, first molars, and second molars of rat pups was completed on the fifteenth day after birth, characterized by the eruption of teeth in the oral cavity [28]. At this point, dental crowns have been formed, so it is possible for calcium level examination [29].…”