Histopathologic Findings Following Scleral Buckling*

Kornblueth, Walter; Behar, Adi; Zauberman, Ch.

doi:10.1016/0002-9394(64)91831-8

Cited by 11 publications

(5 citation statements)

References 2 publications

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“…This was shown in previous studies in which nonabsorbable scleral buckling materials either experimentally or surgically implanted under the conjunctiva became encapsulated [11][12][13][14]. Experimental capsule formation around silicone was observed as early as 3 days after its implantation [15].…”

Section: Capsulementioning

confidence: 66%

Expanded Polytetrafluoroethylene Episcleral Implants Used as Encircling Scleral Buckling

Korobelnik

D’Hermies²,

Chauvaud³

et al. 2000

Ophthalmic Res

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To investigate tissue changes induced by the implantation of expanded polytetrafluoroethylene (e-PTFE) used as encircling scleral buckling, an experimental and histopathological study was performed in rabbits. The eyes of 12 rabbits were implanted during 20–128 days with e-PTFE episcleral implants. Of these, 8 eyes were uncomplicated and enabled us to perform the histopathological study, 2 others were discarded for too short a time of implantation and, in 2 additional eyes, the episcleral implant was exposed with a wide conjunctival erosion. Surrounding the implant, a constant encapsulation was combined with numerous giant cells, forming a granuloma caused by irregularities of the implant outline. Its porous structure allowed a peripheral colonization by fibrovascular tissue. Scleral thinning and scleral invagination were the main scleral changes. No change of the conjunctiva made us suspect that a granuloma occurred before it was found histologically. The granulomatous changes did not seem to modify the apparently good experimental tolerance of the material after its implantation.

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Section: Capsulementioning

confidence: 66%

Expanded Polytetrafluoroethylene Episcleral Implants Used as Encircling Scleral Buckling

Korobelnik

D’Hermies²,

Chauvaud³

et al. 2000

Ophthalmic Res

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“…The two major histological findings in this study are continuous encapsulation surrounding the PCL stents and chronic giant cell granulomatous inflammation beside the explants. The capsule around the episcleral explants was previously demonstrated in several studies 24–27. The tense capsule separates the polymeric stent from surrounding normal tissue and restricts the migration of the explant.…”

Section: Discussionmentioning

confidence: 83%

Biodegradable balloon‐expandable self‐locking polycaprolactone stents as buckling explants for the treatment of retinal detachment: An in vitro and in vivo study

Peng

Liu

et al. 2012

J Biomedical Materials Res

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The purpose of this report was to develop biodegradable balloon-expandable self-locking poly(ε-caprolactone) (PCL) stents for the treatment of retinal detachment. To create the biodegradable stents, polycaprolactone components were first fabricated by a laboratory-scale microinjection molding machine. The components were then assembled into mesh-like stents of 6 and 8 mm in diameter. A special geometry of the components was designed to self-lock the assembled stents after being expanded by balloons. Characterization of the biodegradable PCL stents was carried out. PCL stents exhibited comparable mechanical properties with that of silicone sponge. Neither significant amount of collapse pressure reduction nor weight loss of the stents was observed after being submerged in phosphate buffered saline for 30 days. In addition, the stents were also implanted in the episcleral space of 10 New Zealand white rabbits. The stents were placed in radial direction and left unsutured after balloon expansion. The stents achieved an efficient buckling effect in echographic and fundus photographic examinations. The ocular pressure was significantly elevated after stent implantation and gradually normalized after the second week. The computed tomography studies verified the hypothesis of minimal migration of the PCL stents. The in vivo result suggests that balloon-expandable biodegradable stents can potentially serve as an ideal indenting biomaterial in retinal detachment surgery.

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“…In histopathological studies of eyes treated for retinal detachment (Boniuk & Zimmerman 1961a;1961b, 1965Kornblueth et al 1964;Witschel & Faulhorn 1978;Wilson & Green 1987;Barr 1990), the largest series includes forty-three eyes with silicone and three with polyethylene tubes all obtained from autopsies (Wilson & Green 1987). As in two other studies, the buckling procedure was not much detailed (Witschel & Faulhorn 1978;Barr 1990).…”

Section: Discussionmentioning

confidence: 99%

“…It is difficult to compare the buckling effect of materials different in nature, shape, size, thickness, extensibility, elasticity, hardness, location in the eye, and without information on the tightening of the encircling band. An hourglass shape can be ascribed to such an excessive tightening (Schepens 1983a;Kornblueth et al 1964). Scleral invagination also depends on scleral rigidity, intraocular pressure, and the distance between the material edge and the scleral bite of anchoring sutures (Haynie & D'Amico 1994).…”

Section: Discussionmentioning

confidence: 99%

Scleral and episcleral histological changes related to encircling explants in 20 eyes

D’Hermies

Korobelnik

Chauvaud

et al. 1999

Acta Ophthalmologica Scandinavica

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ABSTRACT.Purpose: To investigate scleral and episcleral histological alterations induced by encircling explants used in scleral buckling procedures. Methods: We performed a histopathological study of 20 enucleated eyes after failure of retinal detachment surgery including encircling scleral buckle. Results: Nonabsorbable materials were encapsulated and often gave rise to a limited scleral invagination. The inner capsular surface was regular in 10 silicone explants, it was partially covered with hydrogel fragments and a granulomatous foreign body giant cell reaction in 8 hydrogel explants. One Arruga thread was encased in fibrosis and a catgut circle showed no encapsulation. Other changes were mostly related to the long-standing retinal detachment: peripheral anterior synechiae, anterior uveal effusion, persistent retinal detachment, retinal gliosis, retinal atrophy, retinal breaks, and silicone oil droplets. Conclusion: All nonabsorbable explants underwent encapsulation and prompted scleral invagination. A granulomatous reaction accompanied hydrogel fragmentation. The long term fragmentation impact on implanted eyes remains unknown.

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Histopathologic Findings Following Scleral Buckling*

Cited by 11 publications

References 2 publications

Expanded Polytetrafluoroethylene Episcleral Implants Used as Encircling Scleral Buckling

Expanded Polytetrafluoroethylene Episcleral Implants Used as Encircling Scleral Buckling

Biodegradable balloon‐expandable self‐locking polycaprolactone stents as buckling explants for the treatment of retinal detachment: An in vitro and in vivo study

Scleral and episcleral histological changes related to encircling explants in 20 eyes

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