Histopathologic evaluation of cutaneous squamous cell carcinoma: Results of a survey among dermatopathologists

Prognostic Criteria for Squamous Cell Cancer of the Skin

“…The importance of tumor thickness and depth is clear in many studies and is the most important tumor factor in the opinion of many authors. Increasing tumor depth correlates with an increased risk for metastases [20]. There was also increased evidence of angiolymphatic and perineural invasion in the nonwell-differentiated tumors compared with the control group of tumors.…”

A clinicopathologic review of lethal nonmelanoma skin cancers in Western Australia

“…12 In North America level of invasion is commonly reported rather than neoplasm thickness for SCC. 32 In this study, we measured level of invasion as used for malignant melanoma 12,13 and by other investigators for SCC. 35,36 Most lethal neoplasms invaded to the subcutis (level 5), 3 of 35 had invaded the reticular dermis, and no level 3 neoplasms resulted in metastasis and death.…”

Introduction to Skin Cancer

“…Histopathologic features have been used to help predict prognosis of SCC. A recent study revealed that histopathologic reporting among dermatopathologists is not uniform, however, with [64].…”