2016
DOI: 10.1111/jre.12402
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Histomorphometric results of different grafting materials and effect of healing time on bone maturation after sinus floor augmentation: a systematic review and meta‐analysis

Abstract: The aim of this systematic review was to evaluate histomorphometric variables, the amount of new bone (NB), residual graft (RG) particles and soft tissue (ST), related to various grafting materials and assess the effect of graft healing time on different histomorphometric outcomes. Studies that were published before October 2015 were electronically and manually searched in three databases. We included human studies that reported the amount of NB, RG and ST in the biopsies taken from the grafted sinuses. Based … Show more

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Cited by 110 publications
(156 citation statements)
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References 67 publications
(80 reference statements)
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“…Bone engineering makes refractory bone defect reconstruction feasible and the key lies in the selection of seed cells . Multiple studies have demonstrated that SMSCs possess the extensive proliferative ability and multilineage differentiation potential . Our current study demonstrated that SMSCs were similar to other stem cells in terms of immunophenotypes and could be differentiated into osteoblasts in vitro.…”
Section: Discussionsupporting
confidence: 53%
“…Bone engineering makes refractory bone defect reconstruction feasible and the key lies in the selection of seed cells . Multiple studies have demonstrated that SMSCs possess the extensive proliferative ability and multilineage differentiation potential . Our current study demonstrated that SMSCs were similar to other stem cells in terms of immunophenotypes and could be differentiated into osteoblasts in vitro.…”
Section: Discussionsupporting
confidence: 53%
“…An optimal bone substitute biomaterial should act as a temporary scaffold for supporting the adhesion, growth, proliferation, and differentiation of the “seed” cells and should also degrade into nontoxic products that can be metabolized via physiological mechanisms . Osseoconductive materials (materials that enhance bone formation on their surface), including freeze‐dried bone allograft (FDBA), demineralized freeze‐dried bone allograft (DFDBA), xenografts produced from bovine bone (BB), porcine bone (PB), and alloplastic materials (β‐tricalcium phosphate [TCP] and hydroxyapatite [HA]), as well as combinations such as that of HA and α‐ and β‐tricalcium phosphate (β‐TCP) may allow new bone formation, thus constituting a scaffold that serves to stabilize the bone clot and support bone growth during the early healing phase . Recently, osteoinductive materials, including scaffolds enriched with recombinant osteoinductive factors (such as bone morphogenetic protein‐2 [rhBMP‐2]) have been claimed to enhance bone formation by stimulating the bone regeneration process .…”
Section: Introductionmentioning
confidence: 99%
“…The maxillary sinus elevation procedure is currently considered the most predictable of pre-prosthetic surgical techniques. Maxillary sinus grafting, combined with Schneiderian membrane elevation, has been proposed to re-establish the ideal quantity and quality of bone prior to implant [4]. …”
Section: Introductionmentioning
confidence: 99%