Histomorphometric analysis of the effects of calcitonin on alveolar socket repair in diabetic rats

Abstract

In order to make a histomorphometric evaluation of the dental alveolus wound healing in chronic presence of salmoncalcitonin (16UI/Kg) in the diabetic condition, sixty albino rats were utilized. These animals were divided into three groups: control(C), diabetic (D) and calcitonin-treated diabetic (Dca). The D and Dca groups were given a single 45mg/ Kg intraperitonial injection of streptozotocin-STZ. After two weeks, all animals were submitted a tooth extraction of the calcitonin-treated animals altered of wound healing after dental extraction, attenuating the impairment of the bone repair dynamic commonly observed in the diabetic status.