1948
DOI: 10.1016/s0002-9394(48)91295-1
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Histology of the Retina in a Case of Tay-Sachs's Disease*

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Cited by 9 publications
(5 citation statements)
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“…6 Although histopathology studies have not been reported for sialidosis and galactosialidosis, this was clearly described for Tay-Sachs disease. 28 On our literature review of 17 reported sialidosis cases including ophthalmological data, a macular cherry-red spot was often a key finding prompting further metabolic and molecular investigations which ultimately lead to an accurate molecular diagnosis. 4 16-27 As to other ophthalmological features, the data is conflicting.…”
Section: Discussionmentioning
confidence: 99%
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“…6 Although histopathology studies have not been reported for sialidosis and galactosialidosis, this was clearly described for Tay-Sachs disease. 28 On our literature review of 17 reported sialidosis cases including ophthalmological data, a macular cherry-red spot was often a key finding prompting further metabolic and molecular investigations which ultimately lead to an accurate molecular diagnosis. 4 16-27 As to other ophthalmological features, the data is conflicting.…”
Section: Discussionmentioning
confidence: 99%
“…6 Although histopathology studies have not been reported for sialidosis and galactosialidosis, this was clearly described for Tay-Sachs disease. 28 …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…They have been found by Hagedoorn (1940) and by MacMillan (1948) in the cells of the inner nuclear layer. The changes in the glia and mesenchymal cells are secondary.…”
Section: Retinitis Circinatamentioning
confidence: 90%
“…There is loss of Nissl substance. 11 Changes are most readily seen at the macula, where ganglion cells are in greatest number, but degeneration of ganglion cells throughout the retina is proportionately the same (Fig. 2).…”
Section: Commentmentioning
confidence: 97%