Histology and Mechanics of In Vivo Tissue-Engineered Vascular Graft for Children

Pulmonary artery augmentation and aortic valve repair using novel tissue-engineered grafts

“…Furthermore, regarding the strength of TEVGs, Fujita and colleagues 4 reported the mechanical strength of TEVGs. As for the suture retention strength, it was concluded that TEVG, the internal mammary artery, and the saphenous vein almost had the same strength.…”

“… 1 Since 2014, we have been developing tissue-engineered vascular grafts (TEVGs) as alternatives to autologous pericardium for use in congenital heart surgeries, and have reported good results for the same. 2 , 3 , 4 In this study we aimed to investigate the midterm outcomes of PA reconstruction and aortic valve plasty (AVP) with TEVGs.…”

Fabrication and investigation of cardiac patch embedded with gold nanowires for improved myocardial infarction therapeutics

“…The reason for the improved values of Young's modulus in case of chemically cross linked COL-AuNW-CP1 may be the improved interaction between the collagen fibres and gold nanowires due to the chemical crosslinking due to which the tensile stress may have been transferred to the nanofibres of the cardiac patches. When we compared the uniaxial tensile properties and the young's Modulus of innate cardiac tissue [36][37], we found that mechanical properties of engineered cardiac patches matched with that of the innate myocardium. However according to these studies it was noted that a little more mechanical stiffness than native myocardium may provide better attenuation of the engineered cardiac patches.…”

A tissue‐engineered, decellularized, connective tissue membrane for allogeneic arterial patch implantation

“…11 Now, more than five years later, the postoperative course remains excellent. 12 Autologous vascular grafts can be fabricated using connective tissue membranes prepared using the encapsulation phenomenon that occurs when foreign materials are implanted under the skin. However, this process requires at least four weeks.…”

“…We have applied this technology to pulmonary arterial patch augmentation in a 2‐year‐old patient and reported a good clinical course 11 . Now, more than five years later, the postoperative course remains excellent 12 …”