Histology after lumpectomy in women with epithelial atypia on stereotactic vacuum-assisted breast biopsy

Abstract

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Magnetic Resonance Imaging-Guided Core Needle Breast Biopsies Resulting in High-Risk Histopathologic Findings: Upstage Frequency and Lesion Characteristics

“…A study by Polat et al 16 reported a greater upstage rate for mixed ADH/ALH of 18% versus an upstage rate of 12% for ADH alone when analyzing samples from all core needle biopsies, including stereotactic, ultrasonography, and MRI guidance. Graesslin et al 17 showed an upstage rate of 28% for mixed ADH/ALH versus 18% for ADH alone in patients with breast biopsy with stereotactic guidance. A study by Hartmann et al 18 in 2014 showed a subsequent risk of breast cancer in patients with mixed ADH and ALH on core needle biopsy that was similar at 22% compared with an overall risk of 20% for ADH or ALH alone when these lesions are followed up.…”

Flat Epithelial Atypia of the Breast: Pathological-Radiological Correlation

“…Radiologic description of flat epithelial atypia is scant in the literature [14,15]. Flat epithelial atypia most often presents at diagnosis as microcalcifications [4,7,10,14,[16][17][18][19]. Our study shows that pure flat epithe-lial atypia presenting as microcalcifications lacks specific features.…”

Conservative management of screen-detected radial scars: role of mammotome excision

“…Histological assessment may prove problematic given the known interobserver variability in diagnosis of atypical epithelial proliferations. Immunohistochemistry for CK5/6 and oestrogen receptor may be of value in distinguishing between epithelial hyperplasia of usual type and atypia, especially when assessing the limited tissue samples obtained in needle core and vacuum-assisted biopsies 21. Immunohistochemistry for E-cadherin may highlight small foci of LN22 and may also help distinguish LN from areas of artefactual dyscohesion.…”