Histologische Befunde an der Tierhaut nach percutaner Sch�digung durch Flu�s�ure und Hexafluorkiesels�ure

Abstract

Morphological changes in the skin of animals were studied after application of concentrated hydrofluoric and hexafluorosilicic acid. The intact skin was not generally affected by these acids. Areas injured before application of the acid showed, however, a continuous spreading of necrosis in the deeper regions. The first histological changes were noticed 1 h after the application. Such early histological findings could be seen long before any macroscopic reaction. The main characteristic findings were the hypocellular necrosis and edema reaching as far as the subcutis. The necrosis showed sharp leukocyte demarcations.