Abstract:Introduction Palatine and nasopharyngeal tonsils are lymphatic fl esh clusters of tissue of the respiratory and digestive tract's epithelium.There is not much literature pertaining to the histological assessment of resected tonsils though anecdotal case reports of choristoma, squamous cell cysts of the tonsil have been reported which mimicked chronic tonsillitis. Tonsils also are an important site for head and neck cancer in adults.Aim & objective To study the histological features of routine tonsillectomy spe… Show more
“…Tonsil develops from the second pharyngeal pouch, epithelium develops from the ectoderm, and lymphoid tissue from the mesoderm. 1 In our study, histological examination of 154 pediatric tonsils showed no evidence of malignancy or tuberculosis. In a study done by Brien 2 in 2010, malignancy was diagnosed in 0.026% of pediatric patients.…”
Section: Discussionsupporting
confidence: 45%
“…Cartilaginous choristoma in tonsil has been recorded. 1 Osteo-cartilaginous choristoma is very rare in tonsil.…”
Section: Discussionmentioning
confidence: 99%
“…Cost of medical treatment and medicolegal issues have created controversy as to whether routine histopathology is a must or not. original article [1][2][3] Associate Professor, 4…”
Introduction:Making a protocol is a must to overcome the controversy of doing routine histopathological examination of tonsillectomy specimen.
Materials and methods:Histopathological report of 100 consecutive tonsillectomy specimens that reached the pathology department of Saveetha Medical College was analyzed.Results: Histological examination of the 154 pediatric tonsils showed reactive lymphoid hyperplasia in all the patients. One specimen had a small cartilaginous choristoma. In the 46 adult tonsils, there were two lymphoma, one extensive osteocartilaginous choristoma, and one epidermoid cyst of tonsil.
Discussion:As the histopathological examination in the pediatric group did not reveal any finding, it can be done only in patients with risk factors. The adult group showed two cases of Hodgkins lymphoma, one epidermoid cyst of tonsil and one osteocartilaginous choristoma tonsil. Hence, we suggest to continue the practice of routine histopathological analysis in adults.
Conclusion:We suggest continuing the practice of routine histopathological examination of all adult tonsillectomy specimens.
“…Tonsil develops from the second pharyngeal pouch, epithelium develops from the ectoderm, and lymphoid tissue from the mesoderm. 1 In our study, histological examination of 154 pediatric tonsils showed no evidence of malignancy or tuberculosis. In a study done by Brien 2 in 2010, malignancy was diagnosed in 0.026% of pediatric patients.…”
Section: Discussionsupporting
confidence: 45%
“…Cartilaginous choristoma in tonsil has been recorded. 1 Osteo-cartilaginous choristoma is very rare in tonsil.…”
Section: Discussionmentioning
confidence: 99%
“…Cost of medical treatment and medicolegal issues have created controversy as to whether routine histopathology is a must or not. original article [1][2][3] Associate Professor, 4…”
Introduction:Making a protocol is a must to overcome the controversy of doing routine histopathological examination of tonsillectomy specimen.
Materials and methods:Histopathological report of 100 consecutive tonsillectomy specimens that reached the pathology department of Saveetha Medical College was analyzed.Results: Histological examination of the 154 pediatric tonsils showed reactive lymphoid hyperplasia in all the patients. One specimen had a small cartilaginous choristoma. In the 46 adult tonsils, there were two lymphoma, one extensive osteocartilaginous choristoma, and one epidermoid cyst of tonsil.
Discussion:As the histopathological examination in the pediatric group did not reveal any finding, it can be done only in patients with risk factors. The adult group showed two cases of Hodgkins lymphoma, one epidermoid cyst of tonsil and one osteocartilaginous choristoma tonsil. Hence, we suggest to continue the practice of routine histopathological analysis in adults.
Conclusion:We suggest continuing the practice of routine histopathological examination of all adult tonsillectomy specimens.
“…Thus, the knowledge of the histological aspects of tonsils and adenoids and the distribution of immune elements involved in chronic inflammation may lead to the identification of pathogenic pathways of initiation, persistence or remission of lesions. Microscopic evaluation can also improve imaging techniques and treatment criteria, as well as the associated morbidity rate [ 20 ], especially in the conditions in which the impact of the deprivation of the child’s organism of numerous immunocompetent cells by radical surgical technique is not yet known [ 5 ].…”
Chronic palatal and nasopharyngeal inflammations are common lesions in pediatric pathology, with major effects on children’s development. The study included 34 cases of chronic tonsillitis and adenoiditis for which we quantified immunohistochemically and analyzed the distribution of inflammatory elements in the follicular, extrafollicular and epithelial compartments, in relation to the composite histological scores and the clinico-epidemiological profile of the lesions. The cases were more frequent under the age of 10, in female patients, coming from urban areas, with the diagnosis of tonsillitis. B-lymphocytes have been associated with follicular areas in tonsillitis and epithelial areas in adenoiditis. In all compartments, T-lymphocytes were more frequently associated with tonsillitis and plasma cells associated with adenoiditis. Macrophages and dendritic cells had a relatively uniform distribution for the three compartments in all cases. The results obtained indicate different inflammatory phenotypes for chronic tonsillitis and adenoiditis, an aspect that may be useful for stratifying patients for optimal therapy.
“…The usual indication for surgical resection of tonsils is chronic recurrent tonsillitis. Literature also does not indicate the reason behind the fact that only part of the population suffers from recurrent chronic tonsillitis in spite being exposed to similar conditions [1].…”
The usual indication for surgical resection of tonsils is chronic recurrent tonsillitis. Literature also does not indicate the reason behind the fact that only part of the population suffers from recurrent chronic tonsillitis in spite being exposed to similar conditions. This was a prospective study, in which 50 tonsil biopsy samples obtained from chronic tonsillitis patients. Specimens were analysed with rapid urease broth test, HelicotecUT PLUS assay and Toluidine blue staining for presence of Helicobacter pylori. The age ranged from 4 to 34 years. The median age for patients with chronic recurrent tonsillitis was 9.5, 23 (46%) patients were male while 27 (54%) were female, presence of H. pylori by rapid urease broth test, HelicotecUT PLUS assay and Histopathology was 4%. Our analysis revealed that H. pylori did not significantly colonize the tonsils and does not play a role in the pathogenesis or development of chronic tonsillitis. The heterogeneity in study population and methodology may have contributed to the non significant results.
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