2013
DOI: 10.3928/1081597x-20131029-01
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Histological Sections of Corneal Incisions in OCT-Guided Femtosecond Laser Cataract Surgery

Abstract: The OCT-guided femtosecond laser is capable of creating accurate, precise, and histologically demonstrable incisions in preselected intrastromal locations.

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Cited by 13 publications
(9 citation statements)
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“…This may be attributed to the relatively high incidence of posterior wound gape, in which the posterior wound margins were still separated. A high incidence of posterior wound retraction in the femtosecond group may indicate remodeling of the CCI resulting from endothelial cell necrosis, molecular dissociation, and biomechanical and thermal changes from the femtosecond laser [28]. A previous study, using transmission electron microscopy confirmed the difference between femtosecond laser corneal flap formation (necrotic keratocytes) and microkeratome corneal flap formation (keratocyte apoptosis), which may potentially explain the different incidence of posterior wound retraction in this study [29].…”
Section: Investigation Of Clear Corneal Incision Using Sd-octsupporting
confidence: 57%
“…This may be attributed to the relatively high incidence of posterior wound gape, in which the posterior wound margins were still separated. A high incidence of posterior wound retraction in the femtosecond group may indicate remodeling of the CCI resulting from endothelial cell necrosis, molecular dissociation, and biomechanical and thermal changes from the femtosecond laser [28]. A previous study, using transmission electron microscopy confirmed the difference between femtosecond laser corneal flap formation (necrotic keratocytes) and microkeratome corneal flap formation (keratocyte apoptosis), which may potentially explain the different incidence of posterior wound retraction in this study [29].…”
Section: Investigation Of Clear Corneal Incision Using Sd-octsupporting
confidence: 57%
“…High magnification light microscopy revealed complete cuts through several corneal layers with only minimal tissue bridges left in place. 154 This suggests that following corneal incisions created with the femtosecond laser, the eye must be considered "open". We therefore strongly recommend doing laser treatment and the other steps of the procedure in one room and expect that to become the standard of care for patient safety.…”
Section: Appropriate Location Of the Femtosecond Laser Platformmentioning
confidence: 99%
“…Reports on intrastromal LRI are few at this time. Schultz et al154 described the histology of FLACS CCI in an vivo report following enucleation. They intrastromal arcuate incision in a human eye and demonstrated it spared the epithelium and separated the Bowman's layer.…”
mentioning
confidence: 99%
“…Corneal incisions to enter the eye have been shown to be stable and precise. 26 They can be made in a reproducible fashion. Their superiority in terms of wound sealing and therefore safety has not been demonstrated.…”
Section: Discussionmentioning
confidence: 99%