Histological evaluation of immune organs in chicken embryos inoculated with Marek’s disease virus and lymphokines

Ortiz, Martha; Petrone, V. M.; Téllez, G.; Fehérvári, T.

doi:10.1556/004.49.2001.2.5

Cited by 2 publications

(2 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The proportion was expressed as the proportion of the medulla considering the sum in mm of the cortex and medullar width as 100%. The spleen was assessed by counting the number of follicles in at least five microscopic fields (10X) randomly selected along a transversal line crossing the section of the organ (Ortiz et al, 2001). …”

Section: Score Of Lymphoid Tissue Injurymentioning

confidence: 99%

Effects of Glycyrrhizic Acid on Productive and Immune Parameters of Broilers

Ocampo

Gómez-Verduzco

Tapia-Pérez

et al. 2016

Rev. Bras. Cienc. Avic.

View full text Add to dashboard Cite

KeywordsBroiler chickens, growth promotion, immune system, glycyrrhizic acid.Submitted: February/2015 Approved: March/2016 ABSTRACT Considering that glycyrrhizic acid (GRA) has been shown to have in-vitro and in-vivo antiviral activity against a wide range of viruses as well as immunostimulating activity, a trial to evaluate its effects on the performance and the immune response against Newcastle disease of broiler chickens was carried out. The study was performed with oneday-old Ross x Ross broiler chickens. GRA was added to the drinking water throughout the 49-d production cycle at a dose of 0.03%. Sample size of the trial was established in a pilot assay. Results showed that broiler chickens treated with GRA presented better weight gain, final body weight, feed conversion ratio, and lower mortality rate than the non-treated controls. In addition, GRA-treated birds presented higher antibody titers against Newcastle disease virus and more efficient cellular immune response, as demonstrated by the late-hypersensitivity response test. Blood lymphocyte and thrombocyte counts also increased in this group. The histopathological examination of the bursa, spleen, and thymus revealed that only the thymus of the GRA-treated group had a clearly defined increase in cortex thickness on day 49. The bursa showed a higher number of lymphoid lesions in CG on days 21 and 49 compared with the GRA group. These results suggest that GRA has growth promotion properties, which are possibly linked to immunebased effects.

show abstract

Section: Score Of Lymphoid Tissue Injurymentioning

confidence: 99%

Effects of Glycyrrhizic Acid on Productive and Immune Parameters of Broilers

Ocampo

Gómez-Verduzco

Tapia-Pérez

et al. 2016

Rev. Bras. Cienc. Avic.

View full text Add to dashboard Cite

show abstract

“…It turns out that particular parts of thymus and lymphatic follicles of bursa of Fabricius are not stable structures. Changes manifesting as the lymphocyte disappearance have been observed during involution of bursa of Fabricius and thymus, associated with sexual maturation, as well as during viral and bacterial diseases (Milicevic end Milicevic 1993;Ortiz et al 2001;Milicevic et al 2002). Lymphocyte depletion, similar to that taking place during infectious diseases, accompanies stress.…”

Section: Discussionmentioning

confidence: 99%

Reactivity of Spleen Germinal Centres in Immunized and ACTH-treated Chickens

Graczyk¹,

Kuryszko²,

Madej³

2003

Acta Vet. Brno

View full text Add to dashboard Cite

Graczyk S., J. Kuryszko, J. Madej: The Reactivity of Spleen Germinal Centres in Immunized and ACTH-treated Chickens. Acta Vet. Brno 2003, 72: 523-531.The aim of the study was to estimate the reactivity of spleen white pulp structures in chickens immunized with sheep erythrocytes (SRBC) and remaining under the influence of ACTH. The 11-week-old chickens were divided into four groups. Group I constituted the control, while chickens of groups II and IV were immunized with SRBC. Chickens of groups III and IV were given ACTH. The sections of thymus, bursa of Fabricius and spleen were done and used for histological evaluation. The number of germinal centres of the types I and II was estimated on the determined spleen surface.It was shown that after SRBC administration in the thymus cortex and in medulla of bursa of Fabricius, proliferation of lymphoid cells was visible. However, after ACTH administration in the discussed thymus and bursa parts, lymphocyte depletion was observed. Morphometric analysis of the spleen showed that after the administration of SRBC and ACTH there is observed the increase in the number of the type II germinal centres.The results of the study indicated the diversified antigen influence on the morphological picture of the lymphatic organs. They also showed different sensitivity of particular structures to administered ACTH. Moreover, the earlier observations and current results allowed to work out the model of formation and movement of different types of germinal centres in the spleen. Chickens, spleen, germinal centres, ACTH, SRBCNumerous environmental factors evoke in an animal organism a set of functional and morphological changes, called stress by H. Selye. These changes most often lead to an adaptation, making it possible for the organism to survive in the changing conditions. According to Puvadolpirod and Thaxton (2000ab), in birds it is difficult to specify a typical stress picture and predict the course of stress. This results not only from the variety of stressors but most of all, from the character of the reaction, in which main coordination systems of the organism play a dominant part. An important role is played by the endocrine system and its hormones, especially glucocorticoids which, ensuring the development of adaptation, at the same time contribute to protection against excessive activation of endogenous processes which threaten with self-destruction (Tomaszewska and Przekop 1997; M itchell and Kettlewell 1998;Goldstein and McEwen 2002). A prolonged activation of the hypothalamic-pituitary-adrenal axis is responsible, among others, for metabolic changes and changes in cells and tissues of the lymphatic system. It has been shown that both the stressors and parenteral administration of ACTH to birds leads, to clear changes in circulating blood, through activation of the above-

show abstract

Histological evaluation of immune organs in chicken embryos inoculated with Marek’s disease virus and lymphokines

Cited by 2 publications

References 7 publications

Effects of Glycyrrhizic Acid on Productive and Immune Parameters of Broilers

Effects of Glycyrrhizic Acid on Productive and Immune Parameters of Broilers

Reactivity of Spleen Germinal Centres in Immunized and ACTH-treated Chickens

Contact Info

Product

Resources

About