Histological Changes in Rat Testicles Induced by Different Concentration of Cadmium Chloride

Abstract

Cadmium chloride considered the stimulates effect to production of reactive oxygen species and causes tissue damage in various tissue. Thus tis paper for investigation the effect of cadmium chloride and determine the effective tissue and reversible tissue on testicular tissue Fifty Wistar albino rats were used which they were divided into four groups control and three groups by injection intraperitoneally of different concentrations of cadmium chloride (0.5, 1, 2) mg/kg body weight one time in week for two weeks. The result showed significant different between groups according to histopathology and physiology parameters. In conclusion showed the 2 mg/kg body weight one time in week for two weeks causes irreversible toxicity of testis compared with other groups.