Abstract:Aim: Methotrexate, a folic acid antagonist is a chemotherapeutic drug used in the treatment of various inflammatory diseases as well as some cancer types. The purpose of this study; it is the study of the effects of boric acid against the hepatotoxic side effects of methotrexate. Material and Method: Male Wistar albino rats were divided into five groups and each group consisted of six animals. The rats in group 1 were used as a control group. Methotrexate was administered to the rats in group 2 and boric acid … Show more
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