Histological changes associated with fibroadenoma breast

Abstract

Introduction: Being the most common benign tumor of the breast, fibroadenoma show considerable histologic changes. It is important to highlight them as some of the changes are associated with increased risk of breast cancer. Aims and Objectives: To study the pattern and histologic changes in fibroadenoma breast. Materials and Methods: Retrospective analysis of histopathology of 55 cases of fibroadenoma breast diagnosed between Jan 2017 to Jun 2018. The pattern, epithelial and stromal changes were examined. Result: Commonest age group involved was in 3rd decade. Pericanalicular pattern was the predominant pattern. Apocrine and cystic change was the commonest change in epithelium. Two cases (3.6%) showed features of complex fibroadenoma. Three (5.5%) cases showed foci of tubular adenoma. Epithelial hyperplasia was seen in 5(9%) of cases of which 2 were mild, 2 were moderate and one was atypical hyperplasia. Inflammatory infiltrate in stroma was frequently observed. Conclusion: Fibroadenoma showed variety of histological changes of which complex fibroadenoma and epithelial hyperplasia are significantly important which requires appropriate management and follow up.