Histological and mechanical comparison of hydroxyapatite‐coated cobalt‐chrome and titanium implants in the rabbit femur

Abstract

The purpose of this study was to compare hydroxyapatite (HA)-coated titanium (Ti) and HA-coated cobalt-chrome (CoCr) implants in the distal femur of the rabbit by evaluating bone apposition and interfacial shear strength. Bilateral cylindrical implants with a plasma sprayed 50-microns thick HA coating were press-fit into the metaphyseal cancellous bone of the lateral femoral condyles in a transverse fashion, and the animals were sacrificed at 2, 4, and 8 weeks postimplantation. Mechanical strength of the interface between HA and bone was measured using the pushout method. For histologic analysis, the fractional linear extent of bone apposition was quantitated. No differences were found in the interfacial shear strength between the Ti and CoCr at any time period. The amount of bone apposition increased significantly at each time interval for both substrate metals, but there were no significant differences between the two substrates at any of the time periods studied. The HA-coated CoCr implants performed in a similar manner to the HA-coated Ti implants, both mechanically and histologically, suggesting that HA-coated CoCr implants deserve further study as a viable alternative to Ti for the biological fixation of total joint components in orthopaedic surgery.

Macro‐structural effect of metal surfaces treated using computer‐assisted yttrium‐aluminum‐garnet laser scanning on bone–implant fixation

“…In recent years, numerous studies of animals have shown that a calcium hydroxyapatite coating increases bone-implant contact through the preferential deposition of new bone on the surface of the implant and the host bed, with no intervening fibrous tissue. [23][24][25] However, some studies show no significant difference in clinical results between implants with and without hydroxyapatite porous coating. 26 Thus, it is not certain that porous coating with hydroxyapatite is the best solution to the problem of bone-implant interlocking.…”

The effect of beta-tricalcium phosphate on mechanical and thermal performances of poly(lactic acid)

“…Other alloys such as CoCr (8), CoCrMo (6) and stainless steels (9) are used. These metallic alloys are biocompatible but they are not able to induce bone tissue regeneration, so that, these alloys must be subjected to surface treatments to allow osteointegration (10)(11)(12).…”

SEM and 3D synchrotron radiation micro‐tomography in the study of bioceramic scaffolds for tissue‐engineering applications

“…For bone tissue engineering, a wide choice of scaffold materials, including metals (Friedman et al, 1995), natural and synthetic polymers (Heise et al, 1990, Vitale-Brovarone et al, 2005, and glasses has been proposed (Ozawa and Kasugai, 1996), each of them presenting different mechanical, chemical, and biological characteristics. Particular attention has been given to the manufacturing of porous bioceramics that mimic trabecular bone chemistry and structure (Martinetti et al, 2001).…”